Acute lung injury: how macrophages orchestrate resolution of inflammation and tissue repair

S Herold, K Mayer, J Lohmeyer - Frontiers in immunology, 2011 - frontiersin.org
Lung macrophages are long living cells with broad differentiation potential, which reside in
the lung interstitium and alveoli or are organ-recruited upon inflammatory stimuli. A role of …

Exosomes as natural delivery carriers for programmable therapeutic nucleic acid nanoparticles (NANPs)

W Ke, KA Afonin - Advanced drug delivery reviews, 2021 - Elsevier
With recent advances in nanotechnology and therapeutic nucleic acids (TNAs), various
nucleic acid nanoparticles (NANPs) have demonstrated great promise in diagnostics and …

The phagocytic code regulating phagocytosis of mammalian cells

TOJ Cockram, JM Dundee, AS Popescu… - Frontiers in …, 2021 - frontiersin.org
Mammalian phagocytes can phagocytose (ie eat) other mammalian cells in the body if they
display certain signals, and this phagocytosis plays fundamental roles in development, cell …

[HTML][HTML] Extracellular vesicles derived from apoptotic cells: an essential link between death and regeneration

M Li, L Liao, W Tian - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Apoptosis is a universal and continuous event during tissue development, restoration,
repair, and regeneration. Mounting evidence has demonstrated that apoptosis is essential …

Molecular mechanisms of late apoptotic/necrotic cell clearance

IKH Poon, MD Hulett, CR Parish - Cell Death & Differentiation, 2010 - nature.com
Phagocytosis serves as one of the key processes involved in development, maintenance of
tissue homeostasis, as well as in eliminating pathogens from an organism. Under normal …

Extracellular vesicles arising from apoptosis: Forms, functions, and applications

CD Gregory, MP Rimmer - The Journal of Pathology, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are lipid bilayer‐enclosed subcellular bodies produced by most,
if not all cells. Research over the last two decades has recognised the importance of EVs in …

Complement factor H in host defense and immune evasion

R Parente, SJ Clark, A Inforzato, AJ Day - Cellular and Molecular Life …, 2017 - Springer
Complement is the major humoral component of the innate immune system. It recognizes
pathogen-and damage-associated molecular patterns, and initiates the immune response in …

Resolution of inflammation: mechanisms and opportunity for drug development

AL Alessandri, LP Sousa, CD Lucas, AG Rossi… - Pharmacology & …, 2013 - Elsevier
Inflammation is a beneficial host reaction to tissue damage and has the essential primary
purpose of restoring tissue homeostasis. Inflammation plays a major role in containing and …

Genetic and phenotypic attributes of splenic marginal zone lymphoma

F Bonfiglio, A Bruscaggin, F Guidetti… - Blood, The Journal …, 2022 - ashpublications.org
Splenic marginal zone B-cell lymphoma (SMZL) is a heterogeneous clinico-biological entity.
The clinical course is variable, multiple genes are mutated with no unifying mechanism, and …

After cell death: the molecular machinery of efferocytosis

B Moon, S Yang, H Moon, J Lee, D Park - Experimental & Molecular …, 2023 - nature.com
Cells constituting a multicellular organism die in a variety of ways throughout life, and most
of them die via apoptosis under normal conditions. The occurrence of apoptosis is especially …