The burden of comorbidity in people with epilepsy is high. Several diseases, including
depression, anxiety, dementia, migraine, heart disease, peptic ulcers, and arthritis are up to …

Epileptic encephalopathies of infancy and childhood comprise a large, heterogeneous
group of severe epilepsies characterised by several seizure types, frequent epileptiform …

Abstract The International League Against Epilepsy (ILAE) Task Force on Nosology and
Definitions proposes a classification and definition of epilepsy syndromes in the neonate …

Since its first clinical description (on his son) by William James West (1793–1848) in 1841,
and the definition of the classical triad of (1) infantile spasms;(2) hypsarrhythmia, and (3) …

Background Infantile spasms constitutes a severe infantile epilepsy syndrome that is difficult
to treat and has a high morbidity. Hormonal therapies or vigabatrin are the most commonly …

Concepts and terminology for classifying seizures and epilepsies have, until recently, rested
on ideas developed nearly a century ago. In order for clinical epilepsy and practice to benefit …

The current spectrum of disorders associated to clinical spasms with onset in infancy is
wider than previously thought; accordingly, its terminology has changed. Nowadays, the …

Purpose: Infantile spasms is a severe infantile seizure disorder. Several factors affect
developmental outcome, especially the underlying etiology of the spasms. Treatment also …

Infantile spasms (IS) is an early-onset epileptic encephalopathy of unknown etiology in∼
40% of patients. We hypothesized that unexplained IS cases represent a large collection of …

Lennox‐Gastaut syndrome (LGS) is a rare epileptic encephalopathy with a peak age of
onset of 3–5 years of age. Reported prevalence rates for LGS vary widely from 1–10% of all …