The prevalence of obesity, diabetes, non-alcoholic fatty liver disease, and related metabolic
disorders has been steadily increasing in the past few decades. Apart from the …

The peroxisome proliferator-activated receptor γ (PPARγ) is a prototypical member of the
nuclear receptor superfamily and integrates the control of energy, lipid, and glucose …

Prostate cancer (CaP) is the most common adult male cancer in the developed world. The
paucity of biomarkers to predict prostate tumor biology makes it important to identify key …

Ononin is a naturally occurring isoflavone glycoside generally found in various plants like
soybeans, legumes, Chinese licorice, Mongolian milkvetch, kudzu, broccoli, and lupine. The …

The number of people diagnosed with diabetes mellitus and its complications is markedly
increasing worldwide, leading to a worldwide epidemic across all age groups, from children …

In the United States, the prevalence of pediatric overweight, defined by the Centers for
Disease Control as a body mass index (BMI) R95th percentile for age and sex, has more …

Endometrial carcinoma is one of the most common female pelvic malignancies. It is well
known that uterine endometrial cell proliferation is under the control of both estrogen and …

Diabetes is prevailing in pandemic proportions, as nearly half a billion population is affected
by diabetes worldwide. The expenditure on diabetes healthcare is estimated to grow to $845 …

Peroxisome proliferator-activated receptor γ (PPARγ), a member of the ligand-activated
nuclear receptor superfamily, plays a key role in mediating differentiation of adipocytes and …

Germline mutations in the tumor suppressor gene PTEN (protein phosphatase and tensin
homolog located on chromosome ten) predispose to heritable breast cancer. The …