[HTML][HTML] Present and future challenges for the investigation of transgenerational epigenetic inheritance

M Fallet, M Blanc, M Di Criscio, P Antczak… - Environment …, 2023 - Elsevier
Epigenetic pathways are essential in different biological processes and in phenotype-
environment interactions in response to different stressors and they can induce phenotypic …

Endocrine-disrupting chemicals (EDCs) and cancer: new perspectives on an old relationship

R Modica, E Benevento, A Colao - Journal of Endocrinological …, 2023 - Springer
Purpose Environmental endocrine-disrupting chemicals (EDCs) are a mixture of chemical
compounds capable to interfere with endocrine axis at different levels and to which …

Transgenerational effects in DNA methylation, genotoxicity and reproductive phenotype by chronic arsenic exposure

LE Nava-Rivera, ND Betancourt-Martínez… - Scientific reports, 2021 - nature.com
An emerging concern is the influences of early life exposure to environmental toxicants on
offspring characteristics in later life. Since recent evidence suggests a transgenerational …

Water contamination by delorazepam induces epigenetic defects in the embryos of the clawed frog Xenopus laevis

C Fogliano, CM Motta, H Acloque, B Avallone… - Science of the Total …, 2023 - Elsevier
Delorazepam, a derivative of diazepam, is a psychotropic drug belonging to the
benzodiazepine class. Used as a nervous-system inhibitor, it treats anxiety, insomnia, and …

Parental exposure to environmentally relevant concentrations of bisphenol-A bis (diphenyl phosphate) impairs vascular development in offspring through DNA/RNA …

C Wang, J Xu, S Luo, J Huang, D Ji, X Qiu… - Environmental …, 2023 - ACS Publications
Bisphenol-A bis (diphenyl phosphate)(BDP) has been increasingly detected in indoor
environmental and human samples. Little is known about its developmental toxicity …

Genes and the environment in cancer: focus on environmentally induced DNA methylation changes

F Coppedè - Cancers, 2023 - mdpi.com
Cancer has traditionally been viewed as a genetic disorder resulting from the accumulation
of gene mutations, chromosomal rearrangements, and aneuploidies in somatic cells …

Epigenetic response profiles into environmental epigenotoxicant screening and health risk assessment: A critical review

J Hu, Y Yu - Chemosphere, 2019 - Elsevier
The epigenome may be an important interface between exposure to environmental
contaminants and adverse outcome on human health. Many environmental pollutants …

Breast cancer chemotherapeutic options: A general overview on the preclinical validation of a multi-target Ruthenium (III) complex lodged in nucleolipid nanosystems

MG Ferraro, M Piccolo, G Misso, F Maione… - Cells, 2020 - mdpi.com
In this review we have showcased the preclinical development of original amphiphilic
nanomaterials designed for ruthenium-based anticancer treatments, to be placed within the …

Clinical ecology—transforming 21st-century medicine with planetary health in mind

DH Nelson, SL Prescott, AC Logan, JS Bland - Challenges, 2019 - mdpi.com
Four decades ago, several health movements were sprouting in isolation. In 1980, the
environmental group Friends of the Earth expanded the World Health Organization definition …

Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms

WK Pang, E Kuznetsova, H Holota, A De Haze… - Molecular Aspects of …, 2024 - Elsevier
This comprehensive review examines the complex interplay between endocrine disrupting
chemicals (EDCs) and the development of testicular germ cell tumors (TGCTs). Despite the …