[HTML][HTML] Present and future challenges for the investigation of transgenerational epigenetic inheritance
Epigenetic pathways are essential in different biological processes and in phenotype-
environment interactions in response to different stressors and they can induce phenotypic …
environment interactions in response to different stressors and they can induce phenotypic …
Endocrine-disrupting chemicals (EDCs) and cancer: new perspectives on an old relationship
R Modica, E Benevento, A Colao - Journal of Endocrinological …, 2023 - Springer
Purpose Environmental endocrine-disrupting chemicals (EDCs) are a mixture of chemical
compounds capable to interfere with endocrine axis at different levels and to which …
compounds capable to interfere with endocrine axis at different levels and to which …
Transgenerational effects in DNA methylation, genotoxicity and reproductive phenotype by chronic arsenic exposure
LE Nava-Rivera, ND Betancourt-Martínez… - Scientific reports, 2021 - nature.com
An emerging concern is the influences of early life exposure to environmental toxicants on
offspring characteristics in later life. Since recent evidence suggests a transgenerational …
offspring characteristics in later life. Since recent evidence suggests a transgenerational …
Water contamination by delorazepam induces epigenetic defects in the embryos of the clawed frog Xenopus laevis
Delorazepam, a derivative of diazepam, is a psychotropic drug belonging to the
benzodiazepine class. Used as a nervous-system inhibitor, it treats anxiety, insomnia, and …
benzodiazepine class. Used as a nervous-system inhibitor, it treats anxiety, insomnia, and …
Parental exposure to environmentally relevant concentrations of bisphenol-A bis (diphenyl phosphate) impairs vascular development in offspring through DNA/RNA …
Bisphenol-A bis (diphenyl phosphate)(BDP) has been increasingly detected in indoor
environmental and human samples. Little is known about its developmental toxicity …
environmental and human samples. Little is known about its developmental toxicity …
Genes and the environment in cancer: focus on environmentally induced DNA methylation changes
F Coppedè - Cancers, 2023 - mdpi.com
Cancer has traditionally been viewed as a genetic disorder resulting from the accumulation
of gene mutations, chromosomal rearrangements, and aneuploidies in somatic cells …
of gene mutations, chromosomal rearrangements, and aneuploidies in somatic cells …
Epigenetic response profiles into environmental epigenotoxicant screening and health risk assessment: A critical review
J Hu, Y Yu - Chemosphere, 2019 - Elsevier
The epigenome may be an important interface between exposure to environmental
contaminants and adverse outcome on human health. Many environmental pollutants …
contaminants and adverse outcome on human health. Many environmental pollutants …
Breast cancer chemotherapeutic options: A general overview on the preclinical validation of a multi-target Ruthenium (III) complex lodged in nucleolipid nanosystems
In this review we have showcased the preclinical development of original amphiphilic
nanomaterials designed for ruthenium-based anticancer treatments, to be placed within the …
nanomaterials designed for ruthenium-based anticancer treatments, to be placed within the …
Clinical ecology—transforming 21st-century medicine with planetary health in mind
DH Nelson, SL Prescott, AC Logan, JS Bland - Challenges, 2019 - mdpi.com
Four decades ago, several health movements were sprouting in isolation. In 1980, the
environmental group Friends of the Earth expanded the World Health Organization definition …
environmental group Friends of the Earth expanded the World Health Organization definition …
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms
WK Pang, E Kuznetsova, H Holota, A De Haze… - Molecular Aspects of …, 2024 - Elsevier
This comprehensive review examines the complex interplay between endocrine disrupting
chemicals (EDCs) and the development of testicular germ cell tumors (TGCTs). Despite the …
chemicals (EDCs) and the development of testicular germ cell tumors (TGCTs). Despite the …