A systematic review of dietary supplements and alternative therapies for weight loss

JA Batsis, JW Apolzan, PJ Bagley, HB Blunt, V Divan… - …, 2021 - Wiley Online Library
Objective Dietary supplements and alternative therapies are commercialized as a panacea
for obesity/weight gain as a result of the minimal regulatory requirements in demonstrating …

Natural products targeting into cancer hallmarks: An update on caffeine, theobromine, and (+)-catechin

FC Cadoná, RF Dantas, GH de Mello… - Critical Reviews in …, 2022 - Taylor & Francis
Natural products have been studied to reveal new therapies against human dysfunctions
since they present several medicinal properties. Caffeine, theobromine and (+)-catechin are …

Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice

Z Wang, T Yang, M Zeng, Z Wang, Q Chen… - Food and Chemical …, 2023 - Elsevier
The main purpose of the present study was to investigate the effect of miquelianin (quercetin
3-O-glucuronide, Q3G), one of the main flavonoids in the Folium Nelumbinis extract (FNE) …

Trans-Cinnamic Acid Stimulates White Fat Browning and Activates Brown Adipocytes

NH Kang, S Mukherjee, JW Yun - Nutrients, 2019 - mdpi.com
Recently, pharmacological activation of brown fat and induction of white fat browning
(beiging) have been considered promising strategies to treat obesity. To search for natural …

Trigonelline induces browning in 3T3‐L1 white adipocytes

M Choi, S Mukherjee, JW Yun - Phytotherapy research, 2021 - Wiley Online Library
Trigonelline, a major alkaloid component of fenugreek, has been demonstrated to have
several biological activities, including antidiabetic and anticancer effects. This study aimed …

Metabolic impact of flavonoids consumption in obesity: from central to peripheral

V Sandoval, H Sanz-Lamora, G Arias, PF Marrero… - Nutrients, 2020 - mdpi.com
The prevention and treatment of obesity is primary based on the follow-up of a healthy
lifestyle, which includes a healthy diet with an important presence of bioactive compounds …

[HTML][HTML] Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure

LL Chen, JQ Huang, YY Wu, LB Chen, SP Li, X Zhang… - Redox Biology, 2021 - Elsevier
Selenoprotein V (SELENOV) is a new and the least conserved member of the selenoprotein
family. Herein we generated Selenov knockout (KO) mice to determine its in vivo function …

Maslinic acid ameliorates inflammation via the downregulation of NF-κB and STAT-1

W Lee, J Kim, EK Park, JS Bae - Antioxidants, 2020 - mdpi.com
Maslinic acid (MA), a natural compound of the triterpenoid group derived from olive,
prevents the generation of pro-inflammatory cytokines and oxidative stress. In human …

Theobromine alleviates diet-induced obesity in mice via phosphodiesterase-4 inhibition

MH Jang, S Mukherjee, MJ Choi, NH Kang… - European journal of …, 2020 - Springer
Purpose Modern science has given much attention to the treatment of obesity by activating
brown adipose tissue (BAT) and browning of white adipose tissue (WAT). Recent studies …

Mitophagy suppression by miquelianin‐rich lotus leaf extract induces 'beiging'of white fat via AMPK/DRP1‐PINK1/PARKIN signaling axis

Z Wang, T Yang, M Zeng, Z Wang… - Journal of the …, 2024 - Wiley Online Library
Abstract Background Lotus (Nelumbo nucifera) leaf has been described to have anti‐obesity
activity, but the role of white fat 'browning'or 'beiging'in its beneficial metabolic actions …