Inflammation, a self-defensive reaction against various pathogenic stimuli, may become
harmful self-damaging process. Increasing evidence has linked chronic inflammation to a …

▪ Abstract Microglia are the principal immune cells in the central nervous system (CNS) and
have a critical role in host defense against invading microorganisms and neoplastic cells …

Established for 20 years as the definitive virology reference, the two-volume classic Fields
Virology is in its thoroughly revised, updated Fifth Edition. More than 100 world-renowned …

Infection with the human immunodeficiency virus (HIV) results in a profound
immunosuppression due predominantly to a selective depletion of helper/inducer T …

Infection with human immunodeficiency virus type 1 (HIV-1) is frequently complicated in its
late stages by the AIDS dementia complex, a neurological syndrome characterized by …

Human immunodeficiency virus (HIV) is the causative agent of the acquired immune
deficiency syndrome (AIDS). A large number of AIDS patients show evidence of neurologic …

Although a high prevalence of central nervous system disease is seen in persons with the
acquired immunodeficiency syndrome (AIDS), the natural history of brain involvement with …

HIV-associated central nervous system (CNS) injury continues to be clinically significant in
the modern era of HIV infection and therapy. A substantial proportion of patients with …

All presently available replication-competent proviral clones of human immunodeficiency
virus type 1 (HIV-1) are derived from cell culture-amplified virus. Since tissue culture is …

The pathogenesis of central nervous system (CNS) disease in acquired immunodeficiency
syndrome (AIDS) is poorly understood but may be related to specific effects of the immune …