Review of advances in electrospinning-based strategies for spinal cord regeneration

Y Li, T Dong, Z Li, S Ni, F Zhou, OA Alimi, S Chen… - Materials Today …, 2022 - Elsevier
Spinal cord injury (SCI) is a devastating neurological condition, commonly leading to
physical and mental deficiencies, pain, other complications, and even death. Most recently …

[HTML][HTML] A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities

MA Ortega, O Fraile-Martinez, C García-Montero… - Military Medical …, 2023 - Springer
Spinal cord injury (SCI) is a devastating and disabling medical condition generally caused
by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological …

Multimodal therapy strategy based on a bioactive hydrogel for repair of spinal cord injury

EJ Roh, DS Kim, JH Kim, CS Lim, H Choi, SY Kwon… - Biomaterials, 2023 - Elsevier
Traumatic spinal cord injury results in permanent and serious neurological impairment, but
there is no effective treatment yet. Tissue engineering approaches offer great potential for …

Targeted Delivery of RGD-CD146+CD271+ Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Promotes Blood–Spinal Cord Barrier Repair after …

Y Xie, Y Sun, Y Liu, J Zhao, Q Liu, J Xu, Y Qin, R He… - ACS …, 2023 - ACS Publications
Spinal cord injury (SCI) disrupts the blood–spinal cord barrier (BSCB), potentially
exacerbating nerve damage and emphasizing the criticality of preserving the BSCB integrity …

[HTML][HTML] Dental pulp stem cell-derived secretome and its regenerative potential

JK Bar, A Lis-Nawara, PG Grelewski - International Journal of Molecular …, 2021 - mdpi.com
The therapeutic potential of the dental pulp stem (DSC) cell-derived secretome, consisting of
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …

Biomaterials delivery strategies to repair spinal cord injury by modulating macrophage phenotypes

Y Xia, R Yang, H Wang, Y Hou, Y Li… - Journal of Tissue …, 2022 - journals.sagepub.com
Spinal cord injury (SCI) causes tremendous harm to a patient's physical, mental, and
financial health. Moreover, recovery of SCI is affected by many factors, inflammation is one …

[HTML][HTML] Toward the next-generation phyto-nanomedicines: Cell-derived nanovesicles (CDNs) for natural product delivery

C Chen, J Wang, M Sun, J Li, HMD Wang - Biomedicine & …, 2022 - Elsevier
Phytochemicals are plant-derived bioactive compounds, which have been widely used for
therapeutic purposes. Due to the poor water-solubility, low bioavailability and non-specific …

Advances in hydrogels for stem cell therapy: regulation mechanisms and tissue engineering applications

G Liu, Y Zhou, X Zhang, S Guo - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Stem cell therapy has shown unparalleled potential in tissue engineering, but it still faces
challenges in the regulation of the stem cell fate. Inspired by the native stem cell niche, a …

[HTML][HTML] Collagen-based bioinks for regenerative medicine: Fabrication, application and prospective

Z Li, C Ruan, X Niu - Medicine in Novel Technology and Devices, 2023 - Elsevier
In the field of regenerative medicine, the importance of 3D bioprinting is self-evident and
nonnegligible. However, 3D bioprinting technology also requires bioink with excellent …

[HTML][HTML] Spinal cord injury management through the combination of stem cells and implanTable 3d bioprinted platforms

A Zarepour, S Hooshmand, A Gökmen, A Zarrabi… - Cells, 2021 - mdpi.com
Spinal cord injury (SCI) has a major impact on affected patients due to its pathological
consequences and absence of capacity for self-repair. Currently available therapies are …