Genetics of glutamate and its receptors in autism spectrum disorder

S Nisar, AA Bhat, T Masoodi, S Hashem, S Akhtar… - Molecular …, 2022 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by
deficits in social interaction skills, impaired communication, and repetitive and restricted …

Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future

JL Silverman, A Thurm, SB Ethridge… - Genes, brain and …, 2022 - Wiley Online Library
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …

Being versus appearing socially uninterested: Challenging assumptions about social motivation in autism

VK Jaswal, N Akhtar - Behavioral and Brain Sciences, 2019 - cambridge.org
Progress in psychological science can be limited by a number of factors, not least of which
are the starting assumptions of scientists themselves. We believe that some influential …

[HTML][HTML] Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism

NN Parikshak, R Luo, A Zhang, H Won, JK Lowe… - Cell, 2013 - cell.com
Genetic studies have identified dozens of autism spectrum disorder (ASD) susceptibility
genes, raising two critical questions:(1) do these genetic loci converge on specific biological …

Sex differences in autism spectrum disorders

DM Werling, DH Geschwind - Current opinion in neurology, 2013 - journals.lww.com
Sex differences in autism spectrum disorders : Current Opinion in Neurology Sex differences in
autism spectrum disorders : Current Opinion in Neurology Log in or Register Subscribe to …

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

ML Estes, AK McAllister - Nature Reviews Neuroscience, 2015 - nature.com
Increasing evidence points to a central role for immune dysregulation in autism spectrum
disorder (ASD). Several ASD risk genes encode components of the immune system and …

Disentangling the heterogeneity of autism spectrum disorder through genetic findings

SS Jeste, DH Geschwind - Nature Reviews Neurology, 2014 - nature.com
Autism spectrum disorder (ASD) represents a heterogeneous group of disorders, which
presents a substantial challenge to diagnosis and treatment. Over the past decade …

The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models

L Mapelli, T Soda, E D'Angelo, F Prestori - International journal of …, 2022 - mdpi.com
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …

A de novo convergence of autism genetics and molecular neuroscience

N Krumm, BJ O'Roak, J Shendure, EE Eichler - Trends in neurosciences, 2014 - cell.com
Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental
disorders with large genetic components, but identification of pathogenic genes has …

Environmental factors in the development of autism spectrum disorders

LA Sealey, BW Hughes, AN Sriskanda, JR Guest… - Environment …, 2016 - Elsevier
Autism spectrum disorders (ASD) are highly heterogeneous developmental conditions
characterized by deficits in social interaction, verbal and nonverbal communication, and …