[HTML][HTML] Type II secretion system: a magic beanstalk or a protein escalator

M Nivaskumar, O Francetic - … et Biophysica Acta (BBA)-Molecular Cell …, 2014 - Elsevier
Type II protein secretion systems (T2SS) are molecular machines that promote specific
transport of folded periplasmic proteins in Gram-negative bacteria, across a dedicated …

The structure and mechanism of the bacterial type II secretion system

S Naskar, M Hohl, M Tassinari… - Molecular …, 2021 - Wiley Online Library
The type II secretion system (T2SS) is a multi‐protein complex used by many bacteria to
move substrates across their cell membrane. Substrates released into the environment …

Proteomic analysis of the Vibrio cholerae type II secretome reveals new proteins, including three related serine proteases

AE Sikora, RA Zielke, DA Lawrence… - Journal of biological …, 2011 - ASBMB
The type II secretion (T2S) system is responsible for extracellular secretion of a broad range
of proteins, including toxins and degradative enzymes that play important roles in the …

The trans‐envelope architecture and function of the type 2 secretion system: New insights raising new questions

JL Thomassin, J Santos Moreno, I Guilvout… - Molecular …, 2017 - Wiley Online Library
Nanomachines belonging to the type IV filament (Tff) superfamily serve a variety of cellular
functions in prokaryotes, including motility, adhesion, electrical conductance, competence …

Diversification of Campylobacter jejuni flagellar C-ring composition impacts its structure and function in motility, flagellar assembly, and cellular processes

LD Henderson, TRS Matthews-Palmer, CJ Gulbronson… - MBio, 2020 - Am Soc Microbiol
Bacterial flagella are reversible rotary motors that rotate external filaments for bacterial
propulsion. Some flagellar motors have diversified by recruiting additional components that …

Docking and Assembly of the Type II Secretion Complex of Vibrio cholerae

SR Lybarger, TL Johnson, MD Gray… - Journal of …, 2009 - Am Soc Microbiol
Secretion of cholera toxin and other virulence factors from Vibrio cholerae is mediated by the
type II secretion (T2S) apparatus, a multiprotein complex composed of both inner and outer …

A regulatory checkpoint during flagellar biogenesis in Campylobacter jejuni initiates signal transduction to activate transcription of flagellar genes

JM Boll, DR Hendrixson - MBio, 2013 - Am Soc Microbiol
Many polarly flagellated bacteria require similar two-component regulatory systems (TCSs)
and σ54 to activate transcription of genes essential for flagellar motility. Herein, we …

The role of intrinsic disorder and dynamics in the assembly and function of the type II secretion system

S Gu, VE Shevchik, R Shaw, RW Pickersgill… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Many Gram-negative commensal and pathogenic bacteria use a type II secretion system
(T2SS) to transport proteins out of the cell. These exported proteins or substrates play a …

In vivo cross‐linking of EpsG to EpsL suggests a role for EpsL as an ATPase‐pseudopilin coupling protein in the Type II secretion system of Vibrio cholerae

MD Gray, M Bagdasarian, WGJ Hol… - Molecular …, 2011 - Wiley Online Library
The type II secretion system is a multi‐protein complex that spans the cell envelope of Gram‐
negative bacteria and promotes the secretion of proteins, including several virulence factors …

The three-dimensional structure of the cytoplasmic domains of EpsF from the type 2 secretion system of Vibrio cholerae

J Abendroth, DD Mitchell, KV Korotkov… - Journal of structural …, 2009 - Elsevier
The type 2 secretion system (T2SS), a multi-protein machinery that spans both the inner and
the outer membranes of Gram-negative bacteria, is used for the secretion of several critically …