Efficacy evaluation, active ingredients, and multitarget exploration of herbal medicine

J Ren, L Yang, S Qiu, AH Zhang, XJ Wang - Trends in Endocrinology & …, 2023 - cell.com
Evidence shows that herbal medicine (HM) could be beneficial for the treatment of various
diseases. However, complexities present in HM due to the unclear bioactive compounds …

[HTML][HTML] Therapeutic mechanisms of traditional Chinese medicine to improve metabolic diseases via the gut microbiota

HY Zhang, JX Tian, FM Lian, M Li, WK Liu… - Biomedicine & …, 2021 - Elsevier
Metabolic diseases such as obesity, type 2 diabetes mellitus, and hyperlipidemia are
associated with the dysfunction of gut microbiota. Traditional Chinese medicines (TCMs) …

[HTML][HTML] The interplay between herbal medicines and gut microbiota in metabolic diseases

L Wang, X Gou, Y Ding, J Liu, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Globally, metabolic diseases are becoming a major public health problem. Herbal
medicines are medicinal materials or preparations derived from plants and are widely used …

[HTML][HTML] Construction of a “Bacteria-Metabolites” Co-Expression Network to Clarify the Anti–Ulcerative Colitis Effect of Flavonoids of Sophora flavescens Aiton by …

J Shao, Z Li, Y Gao, K Zhao, M Lin, Y Li… - Frontiers in …, 2021 - frontiersin.org
Ulcerative colitis (UC) is considered an immune disease, which is related to the dysbiosis of
intestinal microbiota and disorders of the host immune system and metabolism. Sophora …

Chemical diversity, biological activities and Traditional uses of and important Chinese herb Sophora

P Sun, W Zhao, Q Wang, L Chen, K Sun, Z Zhan… - Phytomedicine, 2022 - Elsevier
Abstract Background Sophora flavescens Aiton (SF), also known as Kushen (Chinese: 苦参),
has been an important species in Chinese medicine since the Qin and Han dynasties. It is …

Effects of acylated and nonacylated anthocyanins extracts on gut metabolites and microbiota in diabetic Zucker rats: A metabolomic and metagenomic study

K Chen, X Wei, M Kortesniemi, R Pariyani… - Food Research …, 2022 - Elsevier
Anthocyanins have been shown to have prebiotic properties. This study investigated the
impact of nonacylated anthocyanins and acylated anthocyanins on fecal and cecal …

The alteration in composition and function of gut microbiome in patients with type 2 diabetes

X Zhao, Y Zhang, R Guo, W Yu, F Zhang… - Journal of diabetes …, 2020 - Wiley Online Library
Background. Diabetes mellitus (DM) has become one of the most common chronic
metabolic diseases worldwide. Due to the increasing prevalence and various complications …

[HTML][HTML] Pi-Dan-Jian-Qing decoction ameliorates type 2 diabetes mellitus through regulating the gut microbiota and serum metabolism

X Xie, J Liao, Y Ai, J Gao, J Zhao, F Qu, C Xu… - Frontiers in Cellular …, 2021 - frontiersin.org
Pi-Dan-Jian-Qing decoction (PDJQ) can been used in the treatment of type 2 diabetes
mellitus (T2DM) in clinic. However, the protective mechanisms of PDJQ on T2DM remain …

Dose-dependent effects of lead induced gut injuries: an in vitro and in vivo study

L Yu, Y Yu, R Yin, H Duan, D Qu, F Tian, A Narbad… - Chemosphere, 2021 - Elsevier
Lead (Pb) toxicity has been widely studied, but its dose-dependent toxic effects on the gut
remain unclear, therefore, the aim of this study was to evaluate the effects of different doses …

[HTML][HTML] Serum untargeted metabolomics analysis of the mechanisms of evodiamine on type 2 diabetes mellitus model rats

Y Yu, Q Lu, F Chen, S Wang, C Niu, J Liao, H Wang… - Food & Function, 2022 - pubs.rsc.org
Evodiamine (EVO) is an alkaloid extracted from Evodia rutaecarpa and has various
pharmacological activities, including hypolipidemic, anti-inflammatory, anti-infective, and …