Chemical communication of antibiotic resistance by a highly resistant subpopulation of bacterial cells
OM El-Halfawy, MA Valvano - PloS one, 2013 - journals.plos.org
The overall antibiotic resistance of a bacterial population results from the combination of a
wide range of susceptibilities displayed by subsets of bacterial cells. Bacterial …
wide range of susceptibilities displayed by subsets of bacterial cells. Bacterial …
Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in Pseudomonas aeruginosa
Polymyxins are a last-line therapy against multidrug-resistant Pseudomonas aeruginosa;
however, resistance to polymyxins has been increasingly reported. Therefore …
however, resistance to polymyxins has been increasingly reported. Therefore …
Gram-negative bacterial membrane vesicle release in response to the host-environment: different threats, same trick?
C Volgers, PHM Savelkoul… - Critical Reviews in …, 2018 - Taylor & Francis
Bacteria are confronted with a multitude of stressors when occupying niches within the host.
These stressors originate from host defense mechanisms, other bacteria during niche …
These stressors originate from host defense mechanisms, other bacteria during niche …
Phenotypic and Genome-Wide Analysis of an Antibiotic-Resistant Small Colony Variant (SCV) of Pseudomonas aeruginosa
Background Small colony variants (SCVs) are slow-growing bacteria, which often show
increased resistance to antibiotics and cause latent or recurrent infections. It is therefore …
increased resistance to antibiotics and cause latent or recurrent infections. It is therefore …
Small Is Mighty—Chemical Communication Systems in Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen that causes a variety of acute and
chronic infections. Usually a commensal on the host body, P. aeruginosa is capable of …
chronic infections. Usually a commensal on the host body, P. aeruginosa is capable of …
Exploring glycopeptide-resistance in Staphylococcus aureus: a combined proteomics and transcriptomics approach for the identification of resistance-related markers
A Scherl, P François, Y Charbonnier, JM Deshusses… - BMC genomics, 2006 - Springer
Background To unravel molecular targets involved in glycopeptide resistance, three
isogenic strains of Staphylococcus aureus with different susceptibility levels to vancomycin …
isogenic strains of Staphylococcus aureus with different susceptibility levels to vancomycin …
Alterations of metabolic and lipid profiles in polymyxin-resistant Pseudomonas aeruginosa
Multidrug-resistant Pseudomonas aeruginosa presents a global medical challenge, and
polymyxins are a key last-resort therapeutic option. Unfortunately, polymyxin resistance in P …
polymyxins are a key last-resort therapeutic option. Unfortunately, polymyxin resistance in P …
Polyamines Increase Antibiotic Susceptibility in Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic human pathogen. Treatment is complicated by
frequent acquired resistance to antipseudomonal therapies. Polyamines (cadaverine …
frequent acquired resistance to antipseudomonal therapies. Polyamines (cadaverine …
Antibacterial diamines targeting bacterial membranes
B Wang, B Pachaiyappan, JD Gruber… - Journal of medicinal …, 2016 - ACS Publications
Antibiotic resistance is a growing threat to human health exacerbated by a lack of new
antibiotics. We now describe a series of substituted diamines that produce rapid bactericidal …
antibiotics. We now describe a series of substituted diamines that produce rapid bactericidal …
Transcriptome Analysis of Agmatine and Putrescine Catabolism in Pseudomonas aeruginosa PAO1
Polyamines (putrescine, spermidine, and spermine) are major organic polycations essential
for a wide spectrum of cellular processes. The cells require mechanisms to maintain …
for a wide spectrum of cellular processes. The cells require mechanisms to maintain …