Local inflammation induces complement crosstalk which amplifies the antimicrobial response

J Zhang, J Koh, J Lu, S Thiel, BSH Leong… - PLoS …, 2009 - journals.plos.org
By eliciting inflammatory responses, the human immunosurveillance system notably
combats invading pathogens, during which acute phase proteins (CRP and cytokines) are …

The Pseudomonas aeruginosa PAO1 two-component regulator CarSR regulates calcium homeostasis and calcium-induced virulence factor production through its …

M Guragain, MM King, KS Williamson… - Journal of …, 2016 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic human pathogen that causes severe, life-
threatening infections in patients with cystic fibrosis (CF), endocarditis, wounds, or artificial …

Spermine increases bactericidal activity of silver-nanoparticles against clinical methicillin-resistant Staphylococcus aureus

C Liu, H Shen, S Wang, X Cao, H Xu, Y Xia, T Bai… - Chinese Chemical …, 2018 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) has emerged worldwide as a major
multidrug-resistant pathogen that causes notable morbidity and mortality. Fast emerging of …

Proteomic analysis of nalidixic acid resistance in Escherichia coli: identification and functional characterization of OM proteins

X Lin, H Li, C Wang, X Peng - Journal of proteome research, 2008 - ACS Publications
The worldwide emergence of antibiotic-resistant bacteria poses a serious threat to human
health. To understand the mechanisms of the resistance is extremely important to the control …

Polyamine derivatives: a revival of an old neglected scaffold to fight resistant Gram-negative bacteria?

M Blanchet, D Borselli, JM Brunel - Future medicinal chemistry, 2016 - Taylor & Francis
Emergence of multidrug-resistant pathogens was responsible for microbial infections and
inefficacy of numerous antimicrobial therapies has induced a need for the research of new …

Dynamic proteome response of Pseudomonas aeruginosa to tobramycin antibiotic treatment

X Wu, K Held, C Zheng, BJ Staudinger… - Molecular & Cellular …, 2015 - ASBMB
Genetically susceptible bacteria become antibiotic tolerant during chronic infections, and the
mechanisms responsible are poorly understood. One factor that may contribute to differential …

Functional Characterization of Seven γ-Glutamylpolyamine Synthetase Genes and the bauRABCD Locus for Polyamine and β-Alanine Utilization in Pseudomonas …

X Yao, W He, CD Lu - Journal of bacteriology, 2011 - Am Soc Microbiol
Pseudomonas aeruginosa and many other bacteria can utilize biogenic polyamines,
including diaminopropane (DAP), putrescine (Put), cadaverine (Cad), and spermidine (Spd) …

The roles of microbial cell-cell chemical communication systems in the modulation of antimicrobial resistance

Y Huang, Y Chen, L Zhang - Antibiotics, 2020 - mdpi.com
Rapid emergence of antimicrobial resistance (AMR) has become a critical challenge
worldwide. It is of great importance to understand how AMR is modulated genetically in …

Cell Envelope Stress Response in Pseudomonas aeruginosa

S Chevalier, E Bouffartigues, D Tortuel, A David… - … and Control Strategies, 2022 - Springer
Bacteria sense their environment via the cell envelope, which in Gram-negative bacteria
comprises the outer membrane, the periplasmic space, and the inner membrane …

Reprioritization of biofilm metabolism is associated with nutrient adaptation and long-term survival of Haemophilus influenzae

A Harrison, RL Hardison, RM Wallace, J Fitch… - npj Biofilms and …, 2019 - nature.com
Nontypeable Haemophilus influenzae (NTHI) is a human-restricted pathogen with an
essential requirement for heme–iron acquisition. We previously demonstrated that …