BACKGROUND Metabolic and endocrine alterations in women with polycystic ovary
syndrome (PCOS) affect adipose tissue mass and distribution. PCOS is characterised by …

Background Peroxisomes are single membrane-bound organelles named for their role in
hydrogen peroxide production and catabolism. However, their cellular functions extend well …

Obesity imposes a global health threat and calls for safe and effective therapeutic options.
Here, we found that protein-rich diet significantly reduced body fat storage in fruit flies, which …

Insulin inhibits systemic nonesterified fatty acid (NEFA) flux to a greater degree than glucose
or any other metabolite. This remarkable effect is mainly due to insulin-mediated inhibition of …

The global prevalence of nonalcoholic fatty liver disease (NAFLD) or metabolic associated
fatty liver disease (MAFLD), as it is now known, has gradually increased. NAFLD is a …

Cancer cachexia is a disorder of energy balance characterized by the wasting of adipose
tissue and skeletal muscle resulting in severe weight loss with profound influence on …

Nonalcoholic fatty liver disease (NAFLD) is a common liver disease with a wide spectrum of
liver conditions ranging from hepatic steatosis to nonalcoholic steatohepatitis (NASH) …

Red rice bran extract (RRBE) has been reported to have the potential for in vitro metabolic
modulation and anti-inflammatory properties. However, little is known about the molecular …

Sedentary people have insulin resistance in their skeletal muscle, but whether this also
occurs in fat cells was unknown. Insulin inhibition of hydrolysis of triglycerides (antilipolysis) …

Insulin resistance (IR) refers to a reduction in the ability of insulin to exert its metabolic
effects in organs such as adipose tissue (AT) and skeletal muscle (SM), leading to chronic …