Nebulizers for drug delivery to the lungs

AR Martin, WH Finlay - Expert opinion on drug delivery, 2015 - Taylor & Francis
Introduction: Nebulizers are the oldest modern method of delivering aerosols to the lungs for
the purpose of respiratory drug delivery. While use of nebulizers remains widespread in the …

Inhaled chemotherapy in lung cancer: future concept of nanomedicine

P Zarogoulidis, E Chatzaki, K Porpodis… - International journal …, 2012 - Taylor & Francis
Regional chemotherapy was first used for lung cancer 30 years ago. Since then, new
methods of drug delivery and pharmaceuticals have been investigated in vitro, and in …

Effect of nebulizer type, delivery interface, and flow rate on aerosol drug delivery to spontaneously breathing pediatric and infant lung models

A Ari - Pediatric pulmonology, 2019 - Wiley Online Library
Background Different types of nebulizers, interfaces, and flow rates are used to deliver
aerosolized medications to children. The purpose of this study was to determine the effect of …

In vitro evaluation of aerosols delivered via the nasal route

KK El Taoum, J Xi, JW Kim, A Berlinski - Respiratory Care, 2015 - rc.rcjournal.com
BACKGROUND: Infants and young children are obligate nose breathers; therefore, a
transnasal route seems the logical delivery method of inhaled aerosols. The efficiency of …

Pediatric In Vitro and In Silico Models of Deposition via Oral and Nasal Inhalation

NB Carrigy, CA Ruzycki, L Golshahi… - Journal of Aerosol …, 2014 - liebertpub.com
Respiratory tract deposition models provide a useful method for optimizing the design and
administration of inhaled pharmaceutical aerosols, and can be useful for estimating …

Influence of Aerosol Mask Design on Fugitive Aerosol Concentrations During Nebulization

CE Chiang, HH Li, DD Rowley, TP Fang, HL Lin - Respiratory Care, 2023 - rc.rcjournal.com
BACKGROUND: Secondhand exposure to fugitive aerosols may cause airway diseases in
health providers. We hypothesized that redesigning aerosol masks to be closed-featured …

Nebulized corticosteroids in asthma and COPD. An Italian appraisal

AS Melani - Respiratory care, 2012 - rc.rcjournal.com
Inhaled corticosteroids (ICSs) are the mainstay of anti-inflammatory treatment in subjects
with asthma and COPD. This review evaluates the role of nebulizers as an alternative to …

In vitro comparison of aerosol delivery using different face masks and flow rates with a high-flow humidity system

HL Lin, RJ Harwood, JB Fink, LT Goodfellow… - Respiratory …, 2015 - rc.rcjournal.com
BACKGROUND: Aerosol drug delivery to infants and small children is influenced by many
factors, such as types of interface, gas flows, and the designs of face masks. The purpose of …

Aerosol Delivery of Medication

A Berlinski - Pediatric Pulmonology, 2023 - publications.aap.org
Inhaled therapy is a mainstay of treatment for a wide variety of respiratory diseases in
children. Disease management guidelines recommend inhaled corticosteroids and …

Challenges and opportunities in respiratory drug delivery devices

K Nikander - Expert Opinion on Drug Delivery, 2010 - Taylor & Francis
Recent reviews conclude that there is a need to improve the management of respiratory
diseases treated with inhaled drugs, mainly asthma and chronic obstructive pulmonary …