Ischemic heart disease (IHD) continues to be the most common cause of death globally,
although mortality rates are decreasing with significant advances in treatment. Higher …

Background: It has been suggested that the− 344C/T polymorphism in the CYP11B2 gene is
involved in the development of hypertension. However, the results have been inconsistent …

Objective To develop the missing link between hyperuricemia and hypertension. Methods
The study was conducted in Department of Biochemistry in collaboration with Nephrology …

Hypertension is one of the leading risk factors for mortality. The renin–angiotensin–
aldosterone system (RAAS) is a potent and powerful mediator in the homeostasis of …

目的研究血管紧张素转换酶(ACE) 基因(I/D), 醛固酮合成酶(CYP11B2) 基因-344T/C, α-
内收蛋白(α-ADDUCIN) 基因460G/T 多态性的联合作用与福建汉族原发性高血压的关系 …

В обзоре представлены данные зарубежной и отечественной литературы о
патогенетической роли альдостерона, уровней альдостеронсинтазы и …

Артериальная гипертензия является одной из серьезнейших проблем современного
здравоохранения. Это заболевание является мультифакторным и, как правило …

Hypertension is responsible for a large and increasing proportion of the global disease
burden and is becoming increasingly significant in low-income countries. The aim of this …

Background: Aldosterone synthesized by aldosterone synthase plays an imperative role in
Renin-Angiotensin-Aldosterone System (RAAS). Evidence suggested that aldosterone …

The article presents the data of foreign and national literature on the pathogenetic role of
aldosterone (AL), levels of aldosterone synthase (AS) and gene polymorphisms of this …