Nanostructured drug delivery for better management of tuberculosis

IP Kaur, H Singh - Journal of Controlled Release, 2014 - Elsevier
With almost 30% of the world population suffering from tuberculosis (TB) including its
resurgence in the developed world, better management of this global threat is highly …

Inhaled drug treatment for tuberculosis: Past progress and future prospects

AJ Hickey, PG Durham, A Dharmadhikari… - Journal of Controlled …, 2016 - Elsevier
Since the 1990s the rising incidence of multiple drug resistant TB, particularly in the context
of human immunodeficiency virus co-infected patients, has threatened global TB control. At …

Liposomes for drug delivery to the lungs by nebulization

M Zaru, S Mourtas, P Klepetsanis, AM Fadda… - European Journal of …, 2007 - Elsevier
Preparation of drug-loaded freeze-dried (FD) liposomes, designed for delivery to lungs after
rehydration/nebulization was investigated. Rifampicin (RIF) incorporating multilamelar …

Critical physicochemical and biological attributes of nanoemulsions for pulmonary delivery of rifampicin by nebulization technique in tuberculosis treatment

K Shah, LW Chan, TW Wong - Drug delivery, 2017 - Taylor & Francis
The study investigated aerosolization, pulmonary inhalation, intracellular trafficking potential
in macrophages and pharmacokinetics profiles of rifampicin-oleic acid first-generation …

Macrophage-targeted lipid nanoparticle delivery of microRNA-146a to mitigate hemorrhagic shock-induced acute respiratory distress syndrome

Q Fei, EM Shalosky, R Barnes, VC Shukla, S Xu… - ACS …, 2023 - ACS Publications
The pro-inflammatory response of alveolar macrophages to injurious physical forces during
mechanical ventilation is regulated by the anti-inflammatory microRNA, miR-146a …

[图书][B] Nanoparticle based drug delivery systems for treatment of infectious diseases

M Salouti, A Ahangari - 2014 - books.google.com
The chemotherapy of infections caused by bacteria that inhabit intracellularly presents a
number of uncommon challenges. Many bacteria have found the way to produce a “silent” …

Nanomedicine as a promising strategy for the theranostics of infectious diseases

H Liu, W Zhong, X Zhang, D Lin, J Wu - Journal of Materials Chemistry …, 2021 - pubs.rsc.org
Infectious diseases caused by bacteria, viruses, and fungi and their global spread pose a
great threat to human health. The 2019 World Health Organization report predicted that …

Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis

SM Hwang, DD Kim, SJ Chung, CK Shim - Journal of controlled Release, 2008 - Elsevier
Microspheres containing ofloxacin (HMO) with a mean diameter of 2–5 μm were prepared
by the co-spray drying of ofloxacin and the sodium salt of hyaluronic acid (hyaluronan) …

Physicochemical characterization and stability of rifampicin liposome dry powder formulations for inhalation

N Changsan, HK Chan, F Separovic… - Journal of pharmaceutical …, 2009 - Elsevier
Liposomes were used to encapsulate rifampicin (RIF) as an alternative formulation for
delivery to the respiratory tract. Factors affecting the stability of liposomes containing RIF …

Inhaled Solid Lipid Microparticles to target alveolar macrophages for tuberculosis

E Maretti, T Rossi, M Bondi, MA Croce… - International Journal of …, 2014 - Elsevier
The goal of the work was to evaluate an anti-tubercular strategy based on breathable Solid
Lipid Microparticles (SLM) to target alveolar macrophages and to increase the effectiveness …