Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has emerged as
a robust analytical technique for the rapid and sensitive analysis of diverse biomolecules …

It is challenging to achieve absolute quantitation and accurate identification with mass
spectrometry imaging (MSI) techniques. The issues facing these techniques include the …

Multimodal imaging (MMI) has emerged as a powerful tool in clinical research, combining
different imaging modes to acquire comprehensive information and enabling scientists and …

Analysis of whole animal tissue sections by MALDI MS imaging (MSI) requires effective
sample collection and transfer methods to allow the highest quality of in situ analysis of …

Two of the most promising techniques in terms of ex vivo skin imaging and quantifying are
confocal Raman microscopy and MALDI-TOF mass spectrometry imaging (MALDI-TOF MSI) …

Mass spectrometry (MS) has become the de facto tool for routine quantitative analysis of
biomolecules. MS is increasingly being used to reveal the spatial distribution of proteins …

This work describes the coupling of the IR-MALDESI imaging source with the Q Exactive
mass spectrometer. IR-MALDESI MSI was used to elucidate the spatial distribution of …

Lipid disorders have been associated with glomerulopathies, a distinct type of renal
pathologies, such as nephrotic syndrome. Global analyses targeting kidney lipids in this …

Tissue-specific ion suppression is an unavoidable matrix effect in MALDI mass spectrometry
imaging (MALDI-MSI), the negative impact of which on precision and accuracy in …