Accurate quantitative information of the analytes in mass spectrometry imaging (MSI) is
fundamental for determining the accurate spatial distribution, which can provide additional …

Abstract Knowledge about the region-specific absorption profiles from the gastrointestinal
tract of orally administered drugs is a critical factor guiding dosage form selection in drug …

Drug toxicity observed in animal studies during drug development accounts for the
discontinuation of many drug candidates, with the kidney being a major site of tissue …

There is a high need to develop quantitative imaging methods capable of providing detailed
brain localization information of several molecular species simultaneously. In addition …

Mass spectrometry imaging by Fourier transform ion cyclotron resonance (FT-ICR) yields
hundreds of unique peaks, many of which cannot be resolved by lower performance mass …

Corticosteroids as budesonide can be effective in reducing topic inflammation processes in
different organs. Therapeutic use of budesonide in respiratory diseases, like asthma, chronic …

Mass spectrometry imaging (MSI) provides pharmaceutical researchers with a suite of
technologies to screen and assess compound distributions and relative abundances directly …

Mass spectrometry imaging is employed for mapping proteins, lipids and metabolites in
biological tissues in a morphological context. Although initially developed as a tool for …

Research in the field of neurobiology and neurochemistry has seen a rapid expansion in the
last several years due to advances in technologies and instrumentation, facilitating the …

DNA aneuploidy has been identified as a prognostic factor for epithelial malignancies.
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a …