The role of CXCR3 in DSS-induced colitis

B Chami, AWS Yeung, C van Vreden, NJC King, S Bao - PloS one, 2014 - journals.plos.org
Inflammatory bowel disease (IBD) is a group of disorders that are characterized by chronic,
uncontrolled inflammation in the intestinal mucosa. Although the aetiopathogenesis is poorly …

Prebiotics and synbiotics in ulcerative colitis

A Laurell, K Sjöberg - Scandinavian journal of gastroenterology, 2017 - Taylor & Francis
Background: Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with
unclear pathogenesis. A dysbiotic intestinal microbiota is regarded as a key component in …

Mucin Muc2 deficiency and weaning influences the expression of the innate defense genes Reg3β, Reg3γ and angiogenin-4

N Burger-van Paassen, LMP Loonen, J Witte-Bouma… - PloS one, 2012 - journals.plos.org
Background Mucin Muc2 is the structural component of the intestinal mucus layer. Absence
of Muc2 leads to loss of this layer allowing direct bacterial-epithelial interactions. We …

Administration of Lactobacillus paracasei strains improves immunomodulation and changes the composition of gut microbiota leading to improvement of colitis in mice

WK Kim, YJ Jang, B Seo, DH Han, SJ Park… - Journal of Functional …, 2019 - Elsevier
We confirmed that Lactobacillus paracasei (L. paracasei) strains (KBL382, 384, 385)
exhibited strong protective effects in an in vivo dextran sodium sulfate-induced colitis model …

[HTML][HTML] A theoretical model of temperate phages as mediators of gut microbiome dysbiosis

DM Lin, HC Lin - F1000Research, 2019 - ncbi.nlm.nih.gov
Bacteriophages are the most prominent members of the gut microbiome, outnumbering their
bacterial hosts by a factor of 10. Phages are bacteria-specific viruses that are gaining …

N-acetyldopamine dimer attenuates DSS-induced ulcerative colitis by suppressing NF-κB and MAPK pathways

LJ Huang, YM Wang, LQ Gong, C Hu, Y Gui… - Frontiers in …, 2022 - frontiersin.org
Ulcerative Colitis (UC) is a major form of chronic inflammatory bowel disease of the colonic
mucosa and exhibits progressive morbidity. There is still a substantial need of small …

Intestinal Inflammation and Regeneration–Interdigitating Processes Controlled by Dietary Lipids in Inflammatory Bowel Disease

SJ Kwon, MS Khan, SG Kim - International Journal of Molecular Sciences, 2024 - mdpi.com
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a
disease of chronic inflammatory conditions of the intestinal tract due to disturbance of the …

Lactulose: an indirect antioxidant ameliorating inflammatory bowel disease by increasing hydrogen production

X Chen, Q Zuo, Y Hai, XJ Sun - Medical hypotheses, 2011 - Elsevier
Lactulose, which cannot be digested and absorbed by body, is clinically widely used to treat
constipation and hepatic encephalopathy. Fermented by gastrointestinal tract bacteria …

Probiotics can generate FoxP3 T-cell responses in the small intestine and simultaneously inducing CD4 and CD8 T cell activation in the large intestine

MJ Smelt, BJ de Haan, PA Bron, I van Swam… - PloS one, 2013 - journals.plos.org
Most studies on probiotics aim to restore intestinal homeostasis to reduce immune-
pathology in disease. Of equal importance are studies on how probiotics might prevent or …

Different forms of TFF3 in the human saliva: heterodimerization with IgG Fc binding protein (FCGBP)

T Houben, S Harder, H Schlüter, H Kalbacher… - International journal of …, 2019 - mdpi.com
The peptide TFF3 is a member of a family of secretory lectins, and is typically synthesized by
mucous epithelia together with mucins. It is mainly released from intestinal goblet cells as a …