Invariant natural killer T cells shape the gut microbiota and regulate neutrophil recruitment and function during intestinal inflammation

S Shen, K Prame Kumar, D Stanley, RJ Moore… - Frontiers in …, 2018 - frontiersin.org
Invariant natural killer T (iNKT) cells and neutrophils play an increasingly important part in
the pathogenesis of inflammatory diseases, but their precise roles in modulating colitis …

Altered microbial biogeography in an innate model of colitis

A Boger-May, T Reed, D LaTorre, K Ruley-Haase… - Gut …, 2022 - Taylor & Francis
Changes in the spatial organization, or biogeography, of colonic microbes have been
observed in human inflammatory bowel disease (IBD) and mouse models of IBD. We have …

Ulcerative colitis: pathogenesis

W Fries, S Comunale - Current drug targets, 2011 - ingentaconnect.com
The pathogenesis of ulcerative is still poorly understood. With the introduction of new culture-
independent techniques the research on the intestinal microbiota has revealed an important …

Microbial Imbalance Induces Inflammation by Promoting Salmonella Penetration through the Mucosal Barrier

A Sharma, V Raman, J Lee, NS Forbes - ACS Infectious Diseases, 2022 - ACS Publications
The balance of microbial species in the intestine must be maintained to prevent
inflammation and disease. Healthy bacteria suppress infection by pathogens and prevent …

The SOS response mediates sustained colonization of the mammalian gut

AN Samuels, M Roggiani, J Zhu, M Goulian… - Infection and …, 2019 - Am Soc Microbiol
Bacteria have a remarkable ability to survive, persist, and ultimately adapt to environmental
challenges. A ubiquitous environmental hazard is DNA damage, and most bacteria have …

iNOS-dependent increase in colonic mucus thickness in DSS-colitic rats

O Schreiber, J Petersson, T Walden, D Ahl, S Sandler… - PloS one, 2013 - journals.plos.org
Aim To investigate colonic mucus thickness in vivo in health and during experimental
inflammatory bowel disease. Methods Colitis was induced with 5% DSS in drinking water for …

Gelatin tannate ameliorates acute colitis in mice by reinforcing mucus layer and modulating gut microbiota composition: emerging role for 'gut barrier protectors' in IBD …

F Scaldaferri, LR Lopetuso, V Petito… - United European …, 2014 - journals.sagepub.com
Background Gelatin tannate, a gelatin powder containing tannic acids, is commonly
employed as an intestinal astringent. Neither information nor animal model exist to confirm …

Fluoride-induced alteration in the diversity and composition of bacterial microbiota in mice colon

R Fu, R Niu, R Li, B Yue, X Zhang, Q Cao… - Biological trace element …, 2020 - Springer
Fluoride, as an environmental toxin, causes damage to intestinal mucosa. It may promote
pathogen infection by increasing the intestinal mucosa permeability. In this study, the colonic …

Neonatal hyperoxia disrupts the intestinal barrier and impairs intestinal function in rats

HC Chou, CM Chen - Experimental and molecular pathology, 2017 - Elsevier
Animal studies have demonstrated that neonatal hyperoxia injures the distal small intestine
and disrupts the intestinal barrier. This study evaluated the effects of brief hyperoxia …

Environmental enrichment and gut inflammation modify stress-induced c-Fos expression in the mouse corticolimbic system

F Reichmann, E Painsipp, P Holzer - PloS one, 2013 - journals.plos.org
Environmental enrichment (EE) has a beneficial effect on rodent behaviour, neuronal
plasticity and brain function. Although it may also improve stress coping, it is not known …