[HTML][HTML] Altered mucus glycosylation in core 1 O-glycan-deficient mice affects microbiota composition and intestinal architecture
A functional mucus layer is a key requirement for gastrointestinal health as it serves as a
barrier against bacterial invasion and subsequent inflammation. Recent findings suggest …
barrier against bacterial invasion and subsequent inflammation. Recent findings suggest …
[HTML][HTML] The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium
F Sommer, F Bäckhed - Mucosal immunology, 2015 - Elsevier
The epithelium is a first line of defense against microorganisms in the gut. Reactive oxygen
species (ROS) have an important role in controlling the normal gut microbiota and …
species (ROS) have an important role in controlling the normal gut microbiota and …
Unveiling colitis: a journey through the dextran sodium sulfate-induced model
Animal models of inflammatory bowel disease (IBD) are valuable tools for investigating the
factors involved in IBD pathogenesis and evaluating new therapeutic options. The dextran …
factors involved in IBD pathogenesis and evaluating new therapeutic options. The dextran …
A sticky end for gastrointestinal helminths; the role of the mucus barrier
C Sharpe, DJ Thornton, RK Grencis - Parasite immunology, 2018 - Wiley Online Library
Gastrointestinal (GI) nematodes are a group of successful multicellular parasites that have
evolved to coexist within the intestinal niche of multiple species. It is estimated that over 10 …
evolved to coexist within the intestinal niche of multiple species. It is estimated that over 10 …
[HTML][HTML] The goblet cell-derived mediator RELM-β drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis
Intestinal goblet cells are potentially key players in controlling susceptibility to ulcerative
colitis (UC). Although impaired mucin (Muc2) production by goblet cells increases microbial …
colitis (UC). Although impaired mucin (Muc2) production by goblet cells increases microbial …
[HTML][HTML] Calcium-activated chloride channel regulator 1 (CLCA1) controls mucus expansion in colon by proteolytic activity
EEL Nyström, GMH Birchenough, S van der Post… - …, 2018 - thelancet.com
Many epithelial surfaces of the body are covered with protective mucus, and disrupted
mucus homeostasis is coupled to diseases such as ulcerative colitis, helminth infection …
mucus homeostasis is coupled to diseases such as ulcerative colitis, helminth infection …
Mucus and the goblet cell
MEV Johansson, GC Hansson - Digestive diseases, 2013 - karger.com
The discovery of an inner mucus layer normally impervious to bacteria has changed our way
of understanding the interaction between commensal bacteria and the host epithelial cells …
of understanding the interaction between commensal bacteria and the host epithelial cells …
Fermented Soybean Meal Increases Lactic Acid Bacteria in Gut Microbiota of Atlantic Salmon (Salmo salar)
N Catalán, A Villasante, J Wacyk, C Ramírez… - Probiotics and …, 2018 - Springer
The main goal of the present study was to address the effect of feeding fermented soybean
meal-based diet to Atlantic salmon on gut microbiota. Further, expression of genes of …
meal-based diet to Atlantic salmon on gut microbiota. Further, expression of genes of …
[HTML][HTML] Therapeutic potential to modify the mucus barrier in inflammatory bowel disease
J Sun, X Shen, Y Li, Z Guo, W Zhu, L Zuo, J Zhao, L Gu… - Nutrients, 2016 - mdpi.com
Recently, numerous studies have shown that disruption of the mucus barrier plays an
important role in the exacerbation of inflammatory bowel disease, particularly in ulcerative …
important role in the exacerbation of inflammatory bowel disease, particularly in ulcerative …
Exploring the influence of the gut microbiota and probiotics on health: a symposium report
LV Thomas, T Ockhuizen, K Suzuki - British Journal of Nutrition, 2014 - cambridge.org
The present report describes the presentations delivered at the 7th International Yakult
Symposium,'The Intestinal Microbiota and Probiotics: Exploiting Their Influence on Health' …
Symposium,'The Intestinal Microbiota and Probiotics: Exploiting Their Influence on Health' …