Background Sustained lung inflations (recruitment maneuvers [RMs]) are occasionally used
during mechanical ventilation of patients with acute lung injury to restore aeration to …

Background Alveolar overdistension and repetitive derecruitment-recruitment contribute to
ventilator-induced lung injury (VILI). The authors investigated (1) whether inflammatory cell …

Treppo, Steven, Srboljub M. Mijailovich, and José G. Venegas. Contributions of pulmonary
perfusion and ventilation to heterogeneity in V˙ a/Q˙ measured by PET. J. Appl. Physiol. 82 …

Respiratory gating is the method of dividing the data from a tomographic scan with respect to
the respiratory phase of the patient. It enables more accurate images by reducing the effects …

Background There is limited information on the regional inflammatory effects of mechanical
ventilation and endotoxemia on the production of acute lung injury. Measurement of F …

Heterogeneous, small-airway diameters and alveolar derecruitment in poorly aerated
regions of normal lungs could produce ventilation heterogeneity at those anatomic levels …

Rationale: In a pulmonary process characterized by spatially heterogeneous loss of
aeration, the impairment of gas exchange is expected to depend on the regional distribution …

Dual-energy computed tomography (DECT) can be used for visualization of pulmonary
microvascular contrast material distribution, representing regional perfusion. It is performed …

Background Previous studies have suggested that pulmonary embolism (PE) and
pulmonary artery occlusion result in a shift in alveolar ventilation away from unperfused …

Respiratory motion in PET degrades image quality and limits detectability of small or low-
contrast lesions. Although image quality can be improved using respiratory-gating, this adds …