The role of B cells in atherosclerosis
AP Sage, D Tsiantoulas, CJ Binder… - Nature Reviews Cardiology, 2019 - nature.com
The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …
Oxidized LDL and anti-oxidized LDL antibodies in atherosclerosis–novel insights and future directions in diagnosis and therapy
We provide an up-to-date overview of current topics surrounding oxidized low-density
lipoprotein (oxLDL) and its related antibodies in the quest to better identify the individuals at …
lipoprotein (oxLDL) and its related antibodies in the quest to better identify the individuals at …
Humoral immunity in atherosclerosis and myocardial infarction: from B cells to antibodies
Immune mechanisms are critically involved in the pathogenesis of atherosclerosis and its
clinical manifestations. Associations of specific antibody levels and defined B-cell subsets …
clinical manifestations. Associations of specific antibody levels and defined B-cell subsets …
B cells in atherosclerosis: mechanisms and potential clinical applications
T Pattarabanjird, C Li, C McNamara - Basic to Translational Science, 2021 - jacc.org
Because atherosclerotic cardiovascular disease is a leading cause of death worldwide,
understanding inflammatory processes underpinning its pathology is critical. B cells have …
understanding inflammatory processes underpinning its pathology is critical. B cells have …
The impact of type 2 immunity and allergic diseases in atherosclerosis
N Fernández‐Gallego, R Castillo‐González… - Allergy, 2022 - Wiley Online Library
Allergic diseases are allergen‐induced immunological disorders characterized by the
development of type 2 immunity and IgE responses. The prevalence of allergic diseases has …
development of type 2 immunity and IgE responses. The prevalence of allergic diseases has …
Immunometabolic function of cholesterol in cardiovascular disease and beyond
L Yvan-Charvet, F Bonacina… - Cardiovascular …, 2019 - academic.oup.com
Inflammation represents the driving feature of many diseases, including atherosclerosis,
cancer, autoimmunity and infections. It is now established that metabolic processes shape a …
cancer, autoimmunity and infections. It is now established that metabolic processes shape a …
Anti-oxidized LDL antibodies and coronary artery disease: a systematic review
VJ van den Berg, MM Vroegindewey, I Kardys… - Antioxidants, 2019 - mdpi.com
Antibodies to oxidized LDL (oxLDL) may be associated with improved outcomes in
cardiovascular disease. However, analysis is restricted by heterogenous study design and …
cardiovascular disease. However, analysis is restricted by heterogenous study design and …
Reduction of myocardial ischaemia–reperfusion injury by inactivating oxidized phospholipids
Aims Myocardial ischaemia followed by reperfusion (IR) causes an oxidative burst resulting
in cellular dysfunction. Little is known about the impact of oxidative stress on cardiomyocyte …
in cellular dysfunction. Little is known about the impact of oxidative stress on cardiomyocyte …
Immunodominant MHC-II (major histocompatibility complex II) restricted epitopes in human apolipoprotein B
Background: CD (cluster of differentiation) 4+ T-cell responses to APOB (apolipoprotein B)
are well characterized in atherosclerotic mice and detectable in humans. CD4+ T cells …
are well characterized in atherosclerotic mice and detectable in humans. CD4+ T cells …
Inflammation in HIV and its impact on atherosclerotic cardiovascular disease
LM Obare, T Temu, SA Mallal, CN Wanjalla - Circulation research, 2024 - Am Heart Assoc
People living with HIV have a 1.5-to 2-fold increased risk of developing cardiovascular
disease. Despite treatment with highly effective antiretroviral therapy, people living with HIV …
disease. Despite treatment with highly effective antiretroviral therapy, people living with HIV …