Fight the fire: Association of cytokine genomic markers and suicidal behavior may pave the way for future therapies

X Gonda, G Serafini, P Dome - Journal of personalized medicine, 2023 - mdpi.com
The fight against suicide is highly challenging as it may be one of the most complex and, at
the same time, most threatening among all psychiatric phenomena. In spite of its huge …

Establishing a research agenda for the study and assessment of opioid withdrawal

KE Dunn, EC Strain - The Lancet Psychiatry, 2024 - thelancet.com
The opioid crisis is an international public health concern. Treatments for opioid use
disorder centre largely on the management of opioid withdrawal, an aversive collection of …

Peripheral blood cytokines as potential diagnostic biomarkers of suicidal ideation in patients with first-episode drug-naïve major depressive disorder

Y Xu, J Liang, W Gao, Y Sun, Y Zhang, F Shan… - Frontiers in Public …, 2022 - frontiersin.org
Objective Major Depressive Disorder (MDD) is a leading cause of disability, with a high risk
of suicidal ideation (SI). Few studies have evaluated the potential of multiple cytokines as …

Unlocking the secrets: Exploring the biochemical correlates of suicidal thoughts and behaviors in adults with autism spectrum conditions

IM Cremone, B Nardi, G Amatori, L Palego, D Baroni… - Biomedicines, 2023 - mdpi.com
Involving 1 million people a year, suicide represents one of the major topics of psychiatric
research. Despite the focus in recent years on neurobiological underpinnings …

C-Reactive protein as a potential peripheral biomarker for high-lethality suicide attempts

A Aguglia, A Natale, L Fusar-Poli, GB Gnecco… - Life, 2022 - mdpi.com
The aim of the present study was to identify a cut-off of c-reactive protein (c-RP) potentially
predictive of high-lethality suicide attempts (SA) in an inpatient psychiatric sample. After …

[HTML][HTML] Effects of stress on endophenotypes of suicide across species: A role for ketamine in risk mitigation

SJ Lamontagne, ED Ballard, CA Zarate Jr - Neurobiology of stress, 2022 - Elsevier
Suicide is a leading cause of death and morbidity worldwide, yet few interventions are
available to mitigate its risk. Barriers to effective treatments involve a limited understanding …

High dimensional predictions of suicide risk in 4.2 million US Veterans using ensemble transfer learning

S Dhaubhadel, K Ganguly, RM Ribeiro, JD Cohn… - Scientific reports, 2024 - nature.com
We present an ensemble transfer learning method to predict suicide from Veterans Affairs
(VA) electronic medical records (EMR). A diverse set of base models was trained to predict a …

[HTML][HTML] EEG wakefulness regulation in transdiagnostic patients after a recent suicide attempt

A Rüesch, CT Ip, A Bankwitz, TV de Araujo… - Clinical …, 2023 - Elsevier
Objective Decades of research have not yet produced statistically reliable predictors of
preparatory behavior eventually leading to suicide attempts or deaths by suicide. As the …

Impact of Toxoplasma gondii and Human Microbiome on Suicidal Behavior: A Systematic Review

A Zerekidze, M Li, A Refisch, J Shameya… - Journal of Clinical …, 2024 - mdpi.com
Background: Suicide remains a persistent global health challenge, resisting widespread
prevention efforts. According to previous findings, toxoplasmosis is particularly associated …

[HTML][HTML] Peripheral markers of suicidal behavior: current findings and clinical implications

HJ Kang, JW Kim, SW Kim, JS Han… - Clinical …, 2023 - ncbi.nlm.nih.gov
Biomarkers of suicidal behavior (SB), particularly peripheral biomarkers, may aid in the
development of preventive and intervention strategies. The peripheral biomarkers of SB …