Large-sized bone defects are a great challenge in clinics and considerably impair the quality
of patients' daily life. Tissue engineering strategies using cells, scaffolds, and bioactive …

Biomaterial implantation into the human body plays a key role in the medical field and
biological applications. Increasing the life expectancy of biomaterial implants, reducing the …

Bone defects stand out as one of the greatest challenges of reconstructive surgery. Fused
deposition modelling (FDM) allows for the printing of 3D scaffolds tailored to the morphology …

The host inflammatory response to biomaterials conditions their capacity to promote tissue
repair, and macrophage polarization shift from M1 to M2 is determinant in this process …

Zinc (Zn) is one of the most important trace elements in the human body and plays a key role
in various physiological processes, especially in bone metabolism. Zn-containing materials …

The development of recombinant protein cross-linked injectable hydrogels with good
mechanical strength and effective drug loading capacity for bone regeneration is extremely …

Hydroxyapatite nanoparticles (HApN) are largely employed as osteogenic inorganic
material. Inorganic/polymeric hybrid nanostructures can provide versatile bioactivity for …

Bone regeneration is a vital clinical challenge in massive or complicated bone defects.
Recently, bone tissue engineering has come to the fore to meet the demand for bone repair …

Abstract Hydroxyapatite,(Ca 10 (PO 4) 6 (OH) 2), is a ceramic material similar to the
inorganic part of the bone and can be synthesized in a laboratory environment with different …

At this stage, bone defects caused by trauma, infection, tumor, or congenital diseases are
generally filled with autologous bone or allogeneic bone transplantation, but this treatment …