Decoding sepsis-induced disseminated intravascular coagulation: a comprehensive review of existing and emerging therapies

A Unar, L Bertolino, F Patauner, R Gallo… - Journal of Clinical …, 2023 - mdpi.com
Disseminated intravascular coagulation (DIC) is a recurrent complication of sepsis. Since
DIC not only promotes organ dysfunction but also represents a strong prognostic factor, it is …

Molecular pathways in sepsis pathogenesis: Recent advances and therapeutic avenues

TA Addissouky, IET El Sayed, MMA Ali… - Journal of Cellular …, 2024 - scientificarchives.com
Molecular Pathways in Sepsis Pathogenesis: Recent Advances and Therapeutic Avenues
Loading logo Journals Policies Register Contact Us Special Collections logo Journal of Cellular …

Persistent high sepsis-induced coagulopathy and sequential organ failure assessment scores can predict the 28-day mortality of patients with sepsis: A prospective …

J Li, H Liu, N Wang, F Wang, N Shang, S Guo… - BMC Infectious …, 2024 - Springer
Background The performance of the sepsis-induced coagulopathy (SIC) and sequential
organ failure assessment (SOFA) scores in predicting the prognoses of patients with sepsis …

Consumptive coagulopathy in the ICU

A Retter, BJ Hunt - Hematology, 2023 - ashpublications.org
A consumptive coagulopathy describes a situation where there is a loss of hemostatic
factors, which leads to an increased risk of bleeding. Some recent studies have used the …

A global assessment of coagulation profile and a novel insight into ADAMTS-13 implication in neonatal sepsis

P Papadogeorgou, T Boutsikou, M Boutsikou… - Biology, 2023 - mdpi.com
Simple Summary Coagulation and inflammation are two highly interrelated processes. The
scope of the present study was to investigate the alterations of clotting and anticlotting …

Modulation of Unregulated Inflammation‐Associated Coagulopathy in Sepsis Using Multifunctional Nanosheets

Y Xiao, H Fang, X Wang, M Liu, T Shen… - Advanced Functional …, 2024 - Wiley Online Library
Excessive inflammation‐associated unregulated coagulation leads to disseminated
intravascular coagulation (DIC) and mortality in patients with sepsis worldwide, and current …

The antithrombin activity recovery after substitution therapy is associated with improved 28-day mortality in patients with sepsis-associated disseminated intravascular …

T Iba, T Tanigawa, H Wada, JH Levy - Thrombosis Journal, 2023 - Springer
Background Disseminated intravascular coagulation (DIC) is a common and critical
complication in sepsis. Antithrombin activity, which is considered a biomarker for disease …

Solute Clearance Evaluation and Filter Clotting Prediction in Continuous Renal Replacement Therapy

K Yoshimoto, R Matsuura, Y Komaru… - Journal of Clinical …, 2023 - mdpi.com
Unexpected filter clotting is a major problem in continuous renal replacement therapy
(CRRT). Reduced solute clearance is observed prior to filter clotting. This single-center …

The role of thromboinflammation in acute kidney injury among patients with septic coagulopathy

T Iba, J Helms, CL Maier, M Levi, E Scarlatescu… - Journal of Thrombosis …, 2024 - Elsevier
Inflammation and coagulation are critical self-defense mechanisms for mitigating infection
that can nonetheless induce tissue injury and organ dysfunction. In severe cases, like …

Sepsis-induced coagulopathy (SIC) in the management of sepsis

T Iba, J Helms, JH Levy - Annals of Intensive Care, 2024 - Springer
The mortality rate of sepsis remains high and further increases when complicated by
disseminated intravascular coagulation (DIC). Consequently, early detection and …