The phenomenon of accumulation of senescent adaptive immunity cells in the elderly is
attracting attention due to the increasing risk of global epidemics and aging of the global …

T cell senescence is an indication of T cell dysfunction. The ability of senescent T cells to
respond to cognate antigens is reduced and they are in the late stage of differentiation and …

The geroscience hypothesis proposes biological hallmarks of ageing are modifiable.
Increasing evidence supports targeting these hallmarks with therapeutics could prevent and …

Mass cytometry was employed to investigate 47 circulating leukocyte subsets in patients
with active psoriatic arthritis (PsA, n= 16) compared to healthy controls (n= 13), seropositive …

Human predisposition to neurological diseases such as schizophrenia, Alzheimer's,
Parkinson's and other neuropathologies is associated with genetic and environmental …

The intriguing scientific relationship between autoimmunity and cancer immunology, have
been traditionally indulged to throw spotlight on novel pathological targets. Understandably …

Background This study examined how gut microbiota diversity and richness relate to T cell
aging among 96 healthy adults of all ages. It also explored whether these links differed …

Inflammatory arthritides (IAs), including rheumatoid arthritis (RA) and psoriatic arthritis (PsA),
comprise a heterogeneous group of chronic inflammatory disorders, characterized by the …