Obesity is a disorder with an increasing prevalence, which impairs the life quality of patients
and intensifies societal health care costs. The development of safe and innovative …

Alzheimer's disease (AD) is the foremost type of dementia that afflicts considerable morbidity
and mortality in aged population. Several transcription molecules, pathways, and molecular …

Background Inflammasomes have been found to interact with the gut microbiota, and this
effect is associated with depression, but the mechanisms underlying this interaction have not …

Abstract Type 2 diabetes (T2D) and its target organ injuries cause distressing impacts on
personal health and put an enormous burden on the healthcare system, and increasing …

Background Our previous studies have shown that berberine can improve the nerve function
deficits in ischemic stroke by inhibiting inflammation. The cellular communication between …

Berberine is one of the most important quinoline alkaloids, which has shown numerous
pharmacological activities. There are pieces of evidence that berberine serves as a …

Background Berberine is an isoquinoline alkaloid extracted from various Berberis species
which is widely used in East Asia for a wide range of symptoms. Recently, neuroprotective …

Corydalis yanhusuo WT Wang, also known as yanhusuo, yuanhu, yanhu and xuanhu, is one
of the herb components of many Chinese Traditional Medicine prescriptions such as Jin …

Background: One of the typical symptoms of diabetes mellitus patients was memory
impairment, which was followed by gradual cognitive deterioration and for which there is no …

Significance: Type 2 diabetes mellitus and hyperglycemia can lead to the development of
comorbidities such as atherosclerosis and microvascular/macrovascular complications. Both …