The mechanisms linking obesity to colon cancer: An overview
Obesity, characterised as a chronic low-grade inflammation is a crucial risk factor for colon
cancer. The expansion of the adipose tissue is related to elevated triglyceride and low …
cancer. The expansion of the adipose tissue is related to elevated triglyceride and low …
[HTML][HTML] Development of a colorectal cancer diagnostic model and dietary risk assessment through gut microbiome analysis
J Yang, A McDowell, EK Kim, H Seo, WH Lee… - … & molecular medicine, 2019 - nature.com
Colorectal cancer (CRC) is the third most common form of cancer and poses a critical public
health threat due to the global spread of westernized diets high in meat, cholesterol, and fat …
health threat due to the global spread of westernized diets high in meat, cholesterol, and fat …
[HTML][HTML] Chemoresistance: intricate interplay between breast tumor cells and adipocytes in the tumor microenvironment
I Mentoor, AM Engelbrecht… - Frontiers in …, 2018 - frontiersin.org
Excess adipose tissue is a hallmark of an overweight and/or obese state as well as a
primary risk factor for breast cancer development and progression. In an overweight/obese …
primary risk factor for breast cancer development and progression. In an overweight/obese …
Diet-dependent acid load and the risk of colorectal cancer and adenoma: a case–control study
Objectives: Colorectal cancer (CRC) is the third and second most prevalent cancer in men
and women, respectively. Various epidemiological studies indicated that dietary factors are …
and women, respectively. Various epidemiological studies indicated that dietary factors are …
The anti-oncogenic influence of ellagic acid on colon cancer cells in leptin-enriched microenvironment
AI Yousef, OS El-Masry, EH Yassin - Tumor Biology, 2016 - Springer
Ellagic acid (EA) has been proposed as a promising candidate for therapeutic use in colon
cancer. Investigation of the effectiveness of EA in a leptin-enriched model might have been …
cancer. Investigation of the effectiveness of EA in a leptin-enriched model might have been …
[HTML][HTML] Decreased efficacy of doxorubicin corresponds with modifications in lipid metabolism markers and fatty acid profiles in breast tumors from obese vs. lean mice
I Mentoor, T Nell, Z Emjedi, PJ Van Jaarsveld… - Frontiers in …, 2020 - frontiersin.org
Breast cancer cells modulate lipid and fatty acid metabolism to sustain proliferation. The role
of adipocytes in cancer treatment efficacy remains, however, to be fully elucidated. We …
of adipocytes in cancer treatment efficacy remains, however, to be fully elucidated. We …
[HTML][HTML] Metformin treatment for diabetes mellitus correlates with progression and survival in colorectal carcinoma
MK Powell, D Cempirkova, P Dundr… - Translational …, 2020 - Elsevier
BACKGROUND: Diabetes mellitus is unfavorably associated with cancer risk. The purpose
of this multidisciplinary project was to evaluate a possible association of diabetes mellitus …
of this multidisciplinary project was to evaluate a possible association of diabetes mellitus …
肿瘤相关脂肪微环境与肿瘤的恶性发展
李思憬, 卫晓慧, 何进勇, 袁胜涛, 孙立 - 肿瘤防治研究, 2018 - zlfzyj.com
肿瘤周围脂肪组织可通过激素, 脂肪因子及脂肪酸等生物活性分子与肿瘤细胞产生复杂“对话”,
并在肿瘤增殖, 侵袭及转移等恶性事件中扮演重要角色. 伴随肿瘤发展演化 …
并在肿瘤增殖, 侵袭及转移等恶性事件中扮演重要角色. 伴随肿瘤发展演化 …
Leptin Level Variance in Adults With and Without Cancer
VLR Chatman-Terry - 2019 - search.proquest.com
In 2018, health statistics revealed that, despite the many preventive measures established,
cancer was the second leading cause of death in the United States and the leading cause of …
cancer was the second leading cause of death in the United States and the leading cause of …
Chemoresistance in a breast cancer animal model: the role of obesity and inflammation
I Mentoor - 2019 - scholar.sun.ac.za
Background: Globally an increase in obesity incidence represent a major health concern
amongst a rising incidence of impaired treatment outcomes of breast cancer patients …
amongst a rising incidence of impaired treatment outcomes of breast cancer patients …