Coenzyme A (CoA) is a ubiquitous essential cofactor that plays a central role in the
metabolism of carboxylic acids, including short-and long-chain fatty acids. In the last few …

Two paradigms central to geroscience research are that aging is associated with increased
oxidative stress and increased cancer risk. Therefore, it could be deduced that cancers …

Abstract Place (http://www. dna. affrc. go. jp/htdocs/PLACE/) is a database of nucleotide
sequence motifs found in plant cis-acting regulatory DNA elements. Motifs were extracted …

Abstract Comparison of DNA sequences from different species is a fundamental method for
identifying functional elements in genomes. Here, we describe the VISTA family of tools …

The TRANSFAC® database on eukaryotic transcriptional regulation, comprising data on
transcription factors, their target genes and regulatory binding sites, has been extended and …

Under conditions of limited oxygen availability (hypoxia), multiple cell types release adenine
nucleotides in the form of ATP, ADP, and AMP. Extracellular AMP is metabolized to …

We introduce cap analysis gene expression (CAGE), which is based on preparation and
sequencing of concatamers of DNA tags deriving from the initial 20 nucleotides from 5′ end …

PTEN tumor suppressor is frequently mutated in human cancers and is a negative regulator
of PI3′ K/PKB/Akt-dependent cellular survival. Investigation of the human genomic PTEN …

During the earliest stages of Caenorhabditis elegans embryogenesis, the transcription factor
SKN-1 initiates development of the digestive system and other mesendodermal tissues …

PlantCARE is a database of plant cis-acting regulatory elements, enhancers and repressors.
Besides the transcription motifs found on a sequence, it also offers a link to the EMBL entry …