[HTML][HTML] Challenges and promise of targeting miRNA in rheumatic diseases: A computational approach to identify miRNA association with cell types, cytokines, and …

FS Shaikh, RJ Siegel, A Srivastava, DA Fox… - Frontiers in …, 2024 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNAs that alter the expression of target genes
at the post-transcriptional level, influencing diverse outcomes in metabolism, cell …

miRNA‐Dependent CD4+ T Cell Differentiation in the Pathogenesis of Multiple Sclerosis

J Basak, I Majsterek - Multiple sclerosis international, 2021 - Wiley Online Library
Multiple sclerosis (MS) is characterized by multifocal lesions, chronic inflammatory condition,
and degenerative processes within the central nervous system (CNS) leading to …

Icariin alleviates rheumatoid arthritis via regulating miR-223-3p/NLRP3 signalling axis

ZM Wu, J Luo, XD Shi, SX Zhang, XB Zhu, J Guo - Autoimmunity, 2020 - Taylor & Francis
Rheumatoid arthritis (RA) is considered to be a chronic autoimmune disease, pathogenesis
of RA is complex and effective treatments for RA is still lacking. Previous studies found that …

[HTML][HTML] Circulating microRNAs in young individuals with long-duration type 1 diabetes in comparison with healthy controls

D Swolin-Eide, G Forsander, A Pundziute Lyckå… - Scientific Reports, 2023 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs that are involved in post-transcriptional
control of gene expression and might be used as biomarkers for diabetes-related …

LncRNA ZNF667-AS1 alleviates rheumatoid arthritis by sponging miR-523-3p and inactivating the JAK/STAT signalling pathway

Q Zhuo, L Wei, X Yin, H Li, G Qin, S Li, TT Peng… - …, 2021 - Taylor & Francis
Background Rheumatoid arthritis (RA) is an autoimmune disease, which compromises the
synovial membrane resulting in chronic inflammation. Increasing evidence has …

[HTML][HTML] Serum miRNA-21, miRNA-146a and plasma cell free DNA as novel biomarkers for assessing systemic lupus erythematosus activity

MRK Ibrahim, NGFM Waly, H Moness, SS Ahmed… - Molecular biology …, 2023 - Springer
Background MicroRNA and cell-free DNA have shown significant correlations with several
autoimmune disorders including systemic lupus erythematosus (SLE). SLE has been …

[HTML][HTML] The interplay between transcriptional factors and MicroRNAs as an important factor for Th17/Treg balance in RA patients

T Kmiołek, E Rzeszotarska, A Wajda… - International journal of …, 2020 - mdpi.com
MicroRNAs regulate gene expression of transcriptional factors, which influence Th17/Treg
(regulatory T cells) balance, establishing the molecular mechanism of genetic and …

Enhanced expression of human endogenous retroviruses in new-onset type 1 diabetes: Potential pathogenetic and therapeutic implications

PA Tovo, I Rabbone, D Tinti, I Galliano, M Trada… - …, 2020 - Taylor & Francis
Human endogenous retroviruses (HERVs) have been studied and proposed as relevant
cofactors in several autoimmune diseases, including type 1 diabetes (T1D), though with …

Implication of epigenetic factors in the pathogenesis of type 1 diabetes

J Zhang, LM Chen, Y Zou, S Zhang, F Xiong… - Chinese Medical …, 2021 - mednexus.org
Type 1 diabetes (T1D) is an autoimmune disease that resulted from the severe destruction of
the insulin-producing β cells in the pancreases of individuals with a genetic predisposition …

Circ-UQCRC2 aggravates lipopolysaccharide-induced injury in human bronchial epithelioid cells via targeting miR-495-3p/MYD88-mediated inflammatory response …

X Zhang, C Chen, B Li, W Lu - Autoimmunity, 2021 - Taylor & Francis
Infantile pneumonia is a common inflammatory disease with the infections of various
pathogens in lower respiratory tracts. Here, the role and working mechanism of circular RNA …