The behavioral functions of the cholinergic basalforebrain: lessons from 192 IgG-SAPORIN

CC Wrenn, RG Wiley - International Journal of Developmental …, 1998 - Elsevier
Until recently, our understanding of the functional neuroanatomy of the cholinergicbasal
forebrain (CBF) has been hindered by the lack of a lesioning technique that is truly selective …

A structural basis for memory storage in mammals

NJ Woolf - Progress in neurobiology, 1998 - Elsevier
It is proposed that altered dendrite length and de novo formation of new dendrite branches
in cholinoceptive cells are responsible for long-term memory storage, a process enabled by …

Acetylcholinesterase inhibitors enhance cognitive functions in rats following hypobaric hypoxia

S Muthuraju, P Maiti, P Solanki, AK Sharma… - Behavioural brain …, 2009 - Elsevier
Hypobaric hypoxia (HBH) can produce neuropsychological disorders such as insomnia,
dizziness, memory deficiencies, headache and nausea. It is well known that exposure to …

A new approach to the pharmacological regulation of memory: Sarsasapogenin improves memory by elevating the low muscarinic acetylcholine receptor density in …

Y Hu, Z Xia, Q Sun, A Orsi, D Rees - Brain research, 2005 - Elsevier
The purpose of this paper is to study the basic pharmacological action of sarsasapogenin, a
sapogenin from the Chinese medicinal herb Rhizoma Anemarrhenae,(abbreviated as ZMS …

Loss of calbindin‐D28k from aging human cholinergic basal forebrain: Relation to neuronal loss

C Geula, J Bu, N Nagykery, LFM Scinto… - Journal of …, 2003 - Wiley Online Library
Cholinergic neurons of the basal forebrain (BFCN) are selectively vulnerable in
neurodegenerative disorders of the elderly, particularly in Alzheimer's disease (AD). We …

Changes in the septohippocampal cholinergic system following removal of molar teeth in the aged SAMP8 mouse

M Onozuka, K Watanabe, M Fujita, M Tomida… - Behavioural brain …, 2002 - Elsevier
We investigated the effect of dysfunctional teeth on age-related changes in the
septohippocampal cholinergic system by assessing acetylcholine (ACh) release and choline …

The septo-hippocampal system, learning and recovery of function

G Niewiadomska, M Baksalerska-Pazera… - Progress in Neuro …, 2009 - Elsevier
We understand this review as an attempt to summarize recent advances in the
understanding of cholinergic function in cognition. Such a role has been highlighted in the …

Ex vivo nerve growth factor gene transfer to the basal forebrain in presymptomatic middle-aged rats prevents the development of cholinergic neuron atrophy and …

A Martínez-Serrano, A Björklund - Proceedings of the …, 1998 - National Acad Sciences
Nerve growth factor (NGF) is able to restore spatial learning and reverse forebrain
cholinergic neuron atrophy when administered intracerebrally to behaviorally impaired aged …

Combined lesions of cholinergic and serotonergic neurons in the rat brain using 192 IgG‐saporin and 5, 7‐dihydroxytryptamine: Neurochemical and behavioural …

O Lehmann, H Jeltsch, O Lehnardt… - European Journal of …, 2000 - Wiley Online Library
This study assessed behavioural and neurochemical effects of icv injections of both the
cholinergic toxin 192 IgG‐saporin (2 μg) and the serotonergic toxin 5, 7‐dihydroxytryptamine …

Estrogen modulates spontaneous alternation and the cholinergic phenotype in the basal forebrain

MM Miller, SM Hyder, R Assayag, SR Panarella… - Neuroscience, 1999 - Elsevier
We report that a small population of neurons expresses both choline acetyltransferase and
classical estrogen receptor immunoreactivity and they are found primarily in the bed nucleus …