This study assessed behavioural and neurochemical effects of icv injections of both the
cholinergic toxin 192 IgG‐saporin (2 μg) and the serotonergic toxin 5, 7‐dihydroxytryptamine …

We report that a small population of neurons expresses both choline acetyltransferase and
classical estrogen receptor immunoreactivity and they are found primarily in the bed nucleus …

The cholinergic basal forebrain (CBF) degenerates in Alzheimer's Disease (AD), and the
degree of this degeneration correlates with the degree of dementia. In the present study we …

Targeted cognitive training (TCT) has been reported to improve verbal learning deficits in
patients with schizophrenia (SZ). Despite positive findings, it is not clear whether …

Damage to the basal forebrain frequently results in deficits in learning and memory.
Mnenonic dysfunction also occurs following prolonged ethanol consumption in humans and …

Sigma-1 receptor agonists have recently attracted much attention as potential therapeutic
drugs for cognitive and affective disorders, however, it is still unclear whether they act via …

Saporin, which is extracted from Saponaria officinalis, is a protein toxin that inactivates
ribosomes. Saporin itself is non-selective toxin but acquires high specificity after conjugation …

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to
Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of …

There are indications of a modulatory role carried out by gonadal hormones and pain in
cognitive functions. We have examined this issue in male and female rats by assessing the …

The serotonin 5-HT4 subtype receptor is predominantly localized into anatomical structures
linked to memory and cognition. A few experimental studies report that the acute systemic …