There is considerable interest in utilizing the intracerebroventricular (icv) route of
administration of antibodies in the brain for various studies and for the therapy of …

Impairments in learning and memory, induced by surgical or excitotoxic lesions of the septo‐
hippocampal or basalo‐cortical pathways, can be ameliorated by grafts of cholinergic‐rich …

The primary role of the gonadal steroid hormones in mammals is to regulate reproduction
and related behaviors; however, both androgens and estrogens are also integrally involved …

Alzheimer's disease (AD) is a common neurodegenerative disease. APOE is the strong
genetic risk factor of AD. The existing genome-wide association studies have identified …

Previous experiments on two-way active avoidance have shown conflicting results after
nucleus basalis magnocellularis lesion: disrupting effects with electrolytic lesions and …

Tone paired with stimulation of the nucleus basalis (NB) induces behavioral memory that is
specific to the frequency of the conditioned stimulus (CS), assessed by cardiac and …

Cholinergic neurotransmission is known to affect activity‐dependent plasticity in various
areas, including the visual cortex. However, relatively little is known about the exact role of …

Increases in power and frequency of hippocampal theta activity have been related to
efficient place learning and memory acquisition in hippocampal-dependent tests. The …

Cholinergic medial septal neurons may regulate several aspects of hippocampal function,
including place field stability and spatial working memory. Monkeys with damage to septal …