Inflammation as a driver of adverse left ventricular remodeling after acute myocardial infarction

PC Westman, MJ Lipinski, D Luger, R Waksman… - Journal of the American …, 2016 - jacc.org
Abstract Treatment of acute myocardial infarction (AMI) has improved significantly in recent
years, but many patients have adverse left ventricular (LV) remodeling, a maladaptive …

2017 American College of Rheumatology/American Association of Hip and Knee Surgeons guideline for the perioperative management of antirheumatic medication in …

SM Goodman, B Springer, G Guyatt… - Arthritis & …, 2017 - Wiley Online Library
Objective This collaboration between the American College of Rheumatology and the
American Association of Hip and Knee Surgeons developed an evidence‐based guideline …

Risk of serious infections in tocilizumab versus other biologic drugs in patients with rheumatoid arthritis: a multidatabase cohort study

A Pawar, RJ Desai, DH Solomon, AJS Ortiz… - Annals of the …, 2019 - ard.bmj.com
Objective To investigate the rate of serious bacterial, viral or opportunistic infection in
patients with rheumatoid arthritis (RA) starting tocilizumab (TCZ) versus tumour necrosis …

[HTML][HTML] Systematic review and meta-analysis of serious infections with tofacitinib and biologic disease-modifying antirheumatic drug treatment in rheumatoid arthritis …

V Strand, S Ahadieh, J French, J Geier… - Arthritis research & …, 2015 - Springer
Background Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid
arthritis (RA). Tofacitinib modulates the signaling of cytokines that are integral to lymphocyte …

[HTML][HTML] ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious …

JW Baddley, F Cantini, D Goletti… - Clinical Microbiology …, 2018 - Elsevier
Background The present review is part of the ESCMID Study Group for Infections in
Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and …

The British Society for Rheumatology biologic DMARD safety guidelines in inflammatory arthritis

CR Holroyd, R Seth, M Bukhari, A Malaviya… - …, 2019 - academic.oup.com
Christopher R. Holroyd1, Rakhi Seth1, Marwan Bukhari2, Anshuman Malaviya3, Claire
Holmes1, Elizabeth Curtis4, Christopher Chan1, Mohammed A. Yusuf3, Anna Litwic4, 5 …

[HTML][HTML] Anti-interleukin-1 treatment in patients with rheumatoid arthritis and type 2 diabetes (TRACK): A multicentre, open-label, randomised controlled trial

P Ruscitti, F Masedu, S Alvaro, P Airò… - PLoS …, 2019 - journals.plos.org
Background The inflammatory contribution to type 2 diabetes (T2D) has suggested new
therapeutic targets using biologic drugs designed for rheumatoid arthritis (RA). On this basis …

Alterations in immune function with biologic therapies for autoimmune disease

M Her, A Kavanaugh - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Autoimmune disorders, including rheumatoid arthritis, inflammatory bowel disease,
psoriasis, and others, are characterized by dysregulation of various aspects of normal …

Rheumatoid arthritis and lymphoma: Incidence, pathogenesis, biology, and outcome

A Klein, A Polliack, A Gafter‐Gvili - Hematological oncology, 2018 - Wiley Online Library
Patients with rheumatoid arthritis (RA) have a greater risk of developing both Hodgkin
lymphoma (HL) and non‐HL than the general population. Non‐Hodgkin lymphoma is more …

Clinical pharmacokinetics and pharmacodynamics of monoclonal antibodies approved to treat rheumatoid arthritis

D Ternant, T Bejan-Angoulvant, C Passot… - Clinical …, 2015 - Springer
Monoclonal antibodies (mAbs) are increasingly used to treat rheumatoid arthritis (RA). At
present, anti-tumor necrosis factor-α drugs (infliximab, adalimumab, certolizumab pegol, and …