Objective To estimate the dose–response associations between non-occupational physical
activity and several chronic disease and mortality outcomes in the general adult population …

Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

BACKGROUND Mounting evidence, particularly from prospective epidemiologic studies but
with additional support from animal models and mechanistic studies, supported conclusions …

Obesity is often linked to malignancies including multiple myeloma, and the underlying
mechanisms remain elusive. Here we showed that acetyl-CoA synthetase 2 (ACSS2) may …

Multiple myeloma (MM) is a malignant hematological disease. The disease is characterized
by the clonal proliferation of malignant plasma cells in the bone marrow. MM accounts for …

Multiple myeloma (MM) remains an incurable plasma cell malignancy. Although little is
known about the etiology of MM, several metabolic risk factors such as obesity, diabetes …

Multiple myeloma (MM) is a rare but highly fatal malignancy. High body weight is associated
with this cancer, but several questions remain regarding the aetiological relevance of timing …

Very little is known about the influence of early life exposures on adult cancer risk. The
purpose of this narrative review was to summarize the epidemiologic evidence relating early …

Multiple myeloma (MM) is the second most common hematological malignancy and is
attributed to monoclonal proliferation of plasma cells in the bone marrow. Cancer cells …

Background Obesity is the only known modifiable multiple myeloma (MM) risk factor.
However, the influence of obesity in earlier or later adulthood and the role of other energy …