Disturbances in nitric oxide cycle and related molecular pathways in clear cell renal cell carcinoma

CD Ene, M Tampa, SR Georgescu, C Matei… - Cancers, 2023 - mdpi.com
Simple Summary In this article, we analyze the current state of research on nitric oxide
biosynthesis metabolites in clear cell renal cell carcinoma and the metabolic pathways that …

[HTML][HTML] Recent progress in molecular mechanisms of postoperative recurrence and metastasis of hepatocellular carcinoma

ZS Niu, WH Wang, XJ Niu - World journal of gastroenterology, 2022 - ncbi.nlm.nih.gov
Hepatectomy is currently considered the most effective option for treating patients with early
and intermediate hepatocellular carcinoma (HCC). Unfortunately, the postoperative …

The inflammatory macrophages repress the growth of bone metastatic human prostate cancer cells via TNF-α and IL-6 signaling: Involvement of cell signaling …

M Yamaguchi, K Hashimoto, M Jijiwa, T Murata - Cellular Signalling, 2023 - Elsevier
Macrophages in the cancer microenvironments may play a regulatory role in the progression
and metastasis of prostate cancer cells. However, the crosstalk between macrophages and …

The inflammatory profile orchestrated by inducible nitric oxide synthase in systemic lupus erythematosus

CD Ene, I Nicolae - Journal of Personalized Medicine, 2023 - mdpi.com
(1) Background: The pathogenesis of systemic lupus erythematosus (SLE) involves
complicated and multifactorial interactions. Inducible nitric oxide synthase overactivation …

[HTML][HTML] IL-6 facilitates cross-talk between epithelial cells and tumor-associated macrophages in Helicobacter pylori-linked gastric carcinogenesis

B Yu, D de Vos, X Guo, SF Peng, W Xie… - Neoplasia, 2024 - Elsevier
Purpose Helicobacter pylori (H. pylori) is a significant risk factor for development of gastric
cancer (GC), one of the deadliest malignancies in the world. However, the mechanism by …

[HTML][HTML] The tumor innate immune microenvironment in prostate cancer: an overview of soluble factors and cellular effectors

MT Palano, M Gallazzi, M Cucchiara… - … of Targeted Anti …, 2022 - ncbi.nlm.nih.gov
Prostate cancer (PCa) accounts as the most common non-cutaneous disease affecting
males, and as the first cancer, for incidence, in male. With the introduction of the concept of …

Association between interleukin-6-174G/C gene polymorphism and asthma severity: exploring the role of total serum IgE, blood eosinophils, and FeNO as markers of …

M Al-Ahmad, A Ali, A Maher, MZ Haider - Allergy, Asthma & Clinical …, 2024 - Springer
Background While a connection has been established between serum interleukin-6 (IL-6)
levels and the IL-6 gene (− 174G/C) polymorphism in allergic diseases such as asthma, its …

Improving whole tomato transformation for prostate health: benign prostate hypertrophy as an exploratory model

PG Natali, M Piantelli, M Minacori, M Eufemi… - International Journal of …, 2023 - mdpi.com
It is well-established that the beneficial properties of single phytonutrients can be better
attained when they are taken with the complex of the molecules present in their natural …

Exploratory risk prediction of type II diabetes with isolation forests and novel biomarkers

H Yousef, SF Feng, HF Jelinek - Scientific Reports, 2024 - nature.com
Type II diabetes mellitus (T2DM) is a rising global health burden due to its rapidly increasing
prevalence worldwide, and can result in serious complications. Therefore, it is of utmost …

Angiogenic systemic response to the hypoxic microenvironment in prostate tumorigenesis: A pilot study

C Ene, I Nicolae, CD Ene - … and Therapeutic Medicine, 2023 - spandidos-publications.com
The present paper aimed to investigate the altered angiogenetic mechanisms in hypoxic
conditions in patients with prostate tumours, in correlation with common clinicopathologic …