CONTEXT: Prostate cancer (PCa) is one of the most common human malignancies and
arises through genetic and epigenetic alterations. Epigenetic modifications include DNA …

Somatic embryogenesis (SE) is a powerful tool for plant genetic improvement when used in
combination with traditional agricultural techniques, and it is also an important technique to …

Background: Most biomarkers of exposure tend to have short half-lives. This includes
cotinine, a metabolite of nicotine widely used to assess smoke exposure. Cotinine is thus …

The concept of epigenetics has been known about since the 1940s, but it is only in the last
10 years that research has shown just how wide ranging its effects are. It is now a very …

Prostate, bladder, kidney and testis cancers, the most common genitourinary (GU)
neoplasms, are generally clinically silent at their earliest stages when curative treatment is …

In order to understand whether early epigenetic mechanisms instruct the long-term behavior
of neural stem cells (NSCs) and their progeny, we examined Uhrf1 (ubiquitin-like PHD ring …

Objective The aim of this study is to investigate the potential role of DNA methylation in
mediating the increased risk of developing type 2 diabetes in offspring of mothers who had …

Epigenetics involves a series of mechanisms that entail histone and DNA covalent
modifications and non-coding RNAs, and that collectively contribute to programing cell …

Epigenetics refers to nucleotide sequence-independent events, and heritable changes,
including DNA methylation and histone modification (as the two main processes) …

Background The methylation of DNA is recognized as a key mechanism in the regulation of
genomic stability and evidence for its role in the development of cancer is accumulating …