Where developmental toxicity meets explainable artificial intelligence: state-of-the-art and perspectives

M Vittoria Togo, F Mastrolorito, A Orfino… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction The application of Artificial Intelligence (AI) to predictive toxicology
is rapidly increasing, particularly aiming to develop non-testing methods that effectively …

The Influence of Magnetic Fields, Including the Planetary Magnetic Field, on Complex Life Forms: How Do Biological Systems Function in This Field and in …

DA Hart - Biophysica, 2024 - mdpi.com
Life on Earth evolved to accommodate the biochemical and biophysical boundary conditions
of the planet millions of years ago. The former includes nutrients, water, and the ability to …

An industry-relevant metal mixture, iron status, and reported attention-related behaviors in Italian adolescents

S Schildroth, K Kordas, RF White… - Environmental …, 2024 - ehp.niehs.nih.gov
Background: Exposure to environmental metals has been consistently associated with
attention and behavioral deficits in children, and these associations may be modified by …

Assessing the mediating role of iron status on associations between an industry-relevant metal mixture and verbal learning and memory in Italian adolescents

S Schildroth, L Valeri, K Kordas, B Shi… - Science of The Total …, 2024 - Elsevier
Abstract Background Metals, including lead (Pb), manganese (Mn), chromium (Cr) and
copper (Cu), have been associated with neurodevelopment; iron (Fe) plays a role in the …

Invited Perspective: Studying Metal Impacts on Neurobehavior during the Critical but Challenging Window of Adolescence

CG Howe, HE Laue - Environmental Health Perspectives, 2024 - ehp.niehs.nih.gov
An additional layer of complexity in studying attention during adolescence is the potential for
discrepancies in measures of attention across raters. This was highlighted in the study by …

[HTML][HTML] Blood-cerebrospinal fluid barrier permeability of metals/metalloids and its determinants in pediatric patients

W Wu, X Ruan, C Gu, D Luo, J Ye, F Diao, L Wu… - Ecotoxicology and …, 2023 - Elsevier
Concerns regarding adverse effects of metal/metalloids exposure on brain development and
neurological disorders among children are increasing. However, the transport patterns of …

The FDA's action plan to reduce dietary exposure to arsenic, lead, cadmium, and mercury for infants and young children

ST Mayne - The American Journal of Clinical Nutrition, 2023 - ajcn.nutrition.org
Protecting one of our most vulnerable populations, infants and young children, is among the
FDA's highest priorities, and reducing their exposure to environmental chemical …

Early-life manganese exposure during multiple developmental periods and adolescent verbal learning and memory

A Friedman, S Schildroth, JA Bauer, BA Coull… - Neurotoxicology and …, 2023 - Elsevier
Abstract Background Manganese (Mn) is both an essential and toxic metal, and associations
with neurodevelopment depend on exposure timing. Prospective data examining early life …

Blood Levels of Environmental Heavy Metals are Associated with Poorer Iron Status in Ugandan Children: A Cross-Sectional Study

S Park, E Mupere, TC Lund, JS Hodges, EC Moody… - The Journal of …, 2023 - Elsevier
Background Iron deficiency (ID) and environmental exposure to metals frequently co-occur
among Ugandan children, but little is known about their associations, although iron and …

Association between Prenatal Dietary Toxicants and Infant Neurodevelopment: The Role of Fish

X Kou, N Becerra-Tomás, J Canals, M Bulló, V Arija - Toxics, 2024 - mdpi.com
More research is needed to understand how the maternal consumption of fish and fish-
borne toxicants impacts infant neurodevelopment. The present analysis was conducted over …