[HTML][HTML] Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …
disease. These fungi commonly enter their host via inhalation into the lungs where they …
The molecular basis for the immunogenicity of Cryptococcus neoformans mannoproteins
SM Levitz, CA Specht - FEMS yeast research, 2006 - academic.oup.com
T-cell-mediated immunity is necessary for effective host defenses against infections caused
by Cryptococcus neoformans. Clinical and experimental studies have identified a …
by Cryptococcus neoformans. Clinical and experimental studies have identified a …
The Phenotype of the Cryptococcus-Specific CD4+ Memory T-Cell Response Is Associated With Disease Severity and Outcome in HIV-Associated Cryptococcal …
JN Jarvis, JP Casazza, HH Stone… - The Journal of …, 2013 - academic.oup.com
Background. Correlates of immune protection in patients with human immunodeficiency
virus (HIV)–associated cryptococcal meningitis are poorly defined. A clearer understanding …
virus (HIV)–associated cryptococcal meningitis are poorly defined. A clearer understanding …
Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T cell responses to Cryptococcus neoformans
SM Levitz, S Nong, MK Mansour… - Proceedings of the …, 2001 - National Acad Sciences
The fungus Cryptococcus neoformans is a major cause of morbidity and mortality in patients
with impaired CD4+ T cell function, particularly those with AIDS. To identify cryptococcal …
with impaired CD4+ T cell function, particularly those with AIDS. To identify cryptococcal …
Optimal T cell responses to Cryptococcus neoformans mannoprotein are dependent on recognition of conjugated carbohydrates by mannose receptors
MK Mansour, LS Schlesinger… - The Journal of …, 2002 - journals.aai.org
Cryptococcosis is a leading cause of death among individuals with compromised T cell
function. Soluble Cryptococcus neoformans mannoproteins (MP) have emerged as …
function. Soluble Cryptococcus neoformans mannoproteins (MP) have emerged as …
Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts
CA Specht, CK Lee, H Huang, DJ Tipper, ZT Shen… - MBio, 2015 - Am Soc Microbiol
ABSTRACT A vaccine capable of protecting at-risk persons against infections due to
Cryptococcus neoformans and Cryptococcus gattii could reduce the substantial global …
Cryptococcus neoformans and Cryptococcus gattii could reduce the substantial global …
Role of the Mannose Receptor in a Murine Model of Cryptococcus neoformans Infection
Cryptococcus neoformans is an encapsulated fungal pathogen with a predilection to infect
persons with suppressed T-cell function. Cryptococcal mannoproteins (MP) are highly …
persons with suppressed T-cell function. Cryptococcal mannoproteins (MP) are highly …
Cryptococcosis: clinical and biological aspects
KJ Kwon-Chung, TC Sorrell, F Dromer, E Fung… - Medical …, 2000 - Taylor & Francis
The incidence of cryptococcosis rose dramatically with the advent of the acquired immune
deficiency syndrome (AIDS) epidemic in the early 1980s until the early 1990s. The …
deficiency syndrome (AIDS) epidemic in the early 1980s until the early 1990s. The …
Mannoproteins from Cryptococcus neoformans Promote Dendritic Cell Maturation and Activation
D Pietrella, C Corbucci, S Perito, G Bistoni… - Infection and …, 2005 - Am Soc Microbiol
Our previous data show that mannoproteins (MPs) from Cryptococcus neoformans are able
to induce protective responses against both C. neoformans and Candida albicans. Here we …
to induce protective responses against both C. neoformans and Candida albicans. Here we …
Purification and Characterization of a Second Immunoreactive Mannoprotein from Cryptococcus neoformans That Stimulates T-Cell Responses
C Huang, S Nong, MK Mansour, CA Specht… - Infection and …, 2002 - Am Soc Microbiol
Although T-cell responses are known to be critical for effective host defenses against the
fungal pathogen Cryptococcus neoformans, the antigens that stimulate protective responses …
fungal pathogen Cryptococcus neoformans, the antigens that stimulate protective responses …