This review focuses on the current knowledge of the effects of thyroid hormones on central
nervous system differentiation and development in animals and the human fetal brain. The …

Background Thyroid hormones are critical for early neurocognitive development as well as
growth and development throughout childhood. Prompt recognition and treatment of …

Context Children with congenital hypothyroidism (CH) are at risk for suboptimal
neurodevelopment. Objectives To evaluate neurocognitive function and white matter …

Objective To provide an overview of cognitive and motor outcome, and quality of life (QoL) in
patients with congenital central hypothyroidism (CH-C). Design Systematic review with …

Background Congenital hypothyroidism is one of the most prevalent, albeit preventable
causes of intellectual disability. This study determined the intellectual outcome and health …

En esta segunda parte se abordarán los aspectos del hipotiroidismo congénito (HC): su
etiología, cuadro clínico, diagnóstico, tratamiento y seguimiento. El HC se clasifica, por su …

Context Early treatment of primary congenital hypothyroidism (CH) prevents irreversible
brain damage. Contrary to primary CH, outcome studies on central CH are scarce. Most …

Hypothyroid conditions in early life, if left untreated, are associated with adverse
neurodevelopmental outcomes, including intellectual disability (ID). However, evidence …

Eighty-five percent of the studies of patients with congenital hypothyroidism (CH) treated
with Levothyroxine (L-T4) report neuropsychological sequelae throughout life. In neonates …

Congenital hypothyroidism (CH) is an important cause of preventable intellectual disability.
Implementation of CH neonatal screening programs leading to early treatment has improved …