Immune checkpoint molecules, including inhibitory and stimulatory immune checkpoint
molecules, are defined as ligand–receptor pairs that exert inhibitory or stimulatory effects on …

Abstract B7-H3 (CD276), a member of the B7 family of proteins, is a key player in cancer
progression. This immune checkpoint molecule is selectively expressed in both tumor cells …

Merkel cell carcinoma (MCC)—a neuroendocrine cancer of the skin—is caused by the
integration of Merkel cell polyomavirus and persistent expression of large T antigen and …

B7-H3 belongs to the B7 family of immune checkpoint proteins, which are important
regulators of the adaptive immune response and emerging key players in human cancer. B7 …

Epithelial‑mesenchymal transition (EMT) is a key step in cancer metastasis. B7‑H3, a co‑
signaling molecule associated with poor prognosis of non‑small cell lung cancer (NSCLC) …

Purpose The aim of this study was to explore the potential role of B7-H3 in malignant glioma
progression and identify an innovative approach in clinical glioma therapy. Methods The …

Inhibitory or stimulatory immune checkpoint molecules are expressed on a sizeable fraction
of tumor cells in different tumor types. It was thought that the main function of tumor cell …

The latest advancements in oncology research are focused on autologous immune cell
therapy. However, the effectiveness of this type of immunotherapy for cancer remediation is …

Abstract B7-H3 (CD276 molecule) is an immune checkpoint from the B7 family of molecules
that acts more as a co-inhibitory molecule to promote tumor progression. It is abnormally …

This study was designed to explore the expression of B7‐H3 in human intrahepatic
cholangiocarcinoma (ICC) and its association with the clinicopathologic factors. In the …