Targeting ferroptosis in gastric cancer: Strategies and opportunities
J Le, G Pan, C Zhang, Y Chen, AK Tiwari… - Immunological …, 2024 - Wiley Online Library
Ferroptosis is a novel form of programmed cell death morphologically, genetically, and
biochemically distinct from other cell death pathways and characterized by the accumulation …
biochemically distinct from other cell death pathways and characterized by the accumulation …
Ferritin‐Hijacking Nanoparticles Spatiotemporally Directing Endogenous Ferroptosis for Synergistic Anticancer Therapy
L Zhu, Y You, M Zhu, Y Song, J Zhang, J Hu… - Advanced …, 2022 - Wiley Online Library
Existing ferroptosis as an iron‐dependent form of regulated cell death primarily relies on
importing exogenous iron. However, the excessive employment of toxic materials may cause …
importing exogenous iron. However, the excessive employment of toxic materials may cause …
Metabolism-regulated ferroptosis in cancer progression and therapy
L Ye, X Wen, J Qin, X Zhang, Y Wang, Z Wang… - Cell Death & …, 2024 - nature.com
Cancer metabolism mainly includes carbohydrate, amino acid and lipid metabolism, each of
which can be reprogrammed. These processes interact with each other to adapt to the …
which can be reprogrammed. These processes interact with each other to adapt to the …
[HTML][HTML] Ferroptotic stress promotes macrophages against intracellular bacteria
R Ma, L Fang, L Chen, X Wang, J Jiang, L Gao - Theranostics, 2022 - ncbi.nlm.nih.gov
Rational: Intracellular bacterial survival is a major factor causing chronic or recurrent
infection, leading to the failure of both host defense and/or antibiotic treatment. However, the …
infection, leading to the failure of both host defense and/or antibiotic treatment. However, the …
Hijacking endogenous iron and GSH via a polyvalent ferroptosis agonist to enhance tumor immunotherapy
Y Li, N Lei, X Yao, Y Zhang, Y Dong, J Yi… - Advanced Functional …, 2023 - Wiley Online Library
The clinical application of ferroptosis, characterized by iron‐dependent lipid peroxidation, is
limited because of the serious side effects of using toxic‐dose iron. Herein, a polyvalent …
limited because of the serious side effects of using toxic‐dose iron. Herein, a polyvalent …
Targeted modulation and enhancement of macrophages via sonodynamic therapy-driven cupferroptosis-like stress for implant-associated biofilm infections
As the vanguard against implant-associated infections (IAIs), macrophages facilitate the
phagocytosis and pro-inflammatory polarization of planktonic and biofilm infections, but …
phagocytosis and pro-inflammatory polarization of planktonic and biofilm infections, but …
The role of the ferroptosis pathway in the regulation of polysaccharides for human health: A review
X Niu, Y Yao, Y Li, C Li, X Pan, L Han - International Journal of Biological …, 2023 - Elsevier
Polysaccharides are natural polymers with ketone or aldehyde groups that are widely found
in plants, animals, and microorganisms. They exhibit various biological activities and have …
in plants, animals, and microorganisms. They exhibit various biological activities and have …
[HTML][HTML] Development of chitosan, pullulan, and alginate based drug-loaded nano-emulsions as a potential malignant melanoma delivery platform
GH Fard, Z Moinipoor, S Anastasova-Ivanova… - Carbohydrate Polymer …, 2022 - Elsevier
Melanoma is the most aggressive form of skin cancer and various treatments have been
investigated to treat this disease, but drug resistance remains an important factor in the …
investigated to treat this disease, but drug resistance remains an important factor in the …
Micro ribonucleic acid 27a aggravates ferroptosis during early ischemic stroke of rats through nuclear factor erythroid-2-related factor 2
J Zhang, H Sun, L Zhu, L Du, Y Ma, Y Ma, J Yu, A Meng - Neuroscience, 2022 - Elsevier
Ischaemic stroke (IS) is characterized by high morbidity, disability and mortality and lacks
effective solutions. MiRNA-27a has been implicated in ferroptosis, but evidence that miRNA …
effective solutions. MiRNA-27a has been implicated in ferroptosis, but evidence that miRNA …
Ferroptosis and its Modulators: A Raising Target for Cancer and Alzheimer's Disease
G Singh, P Kesharwani, GK Singh, S Kumar… - Bioorganic & Medicinal …, 2023 - Elsevier
The process of ferroptosis, a recently identified form of regulated cell death (RCD) is
associated with the overloading of iron species and lipid-derived ROS accumulation …
associated with the overloading of iron species and lipid-derived ROS accumulation …