Prostate cancer (PC) is the third-leading cause of cancer-related deaths worldwide.
Although the current treatment strategies are progressing rapidly, PC is still representing a …

The failure of chemotherapy is a major challenge nowadays, and in order to ensure effective
treatment of cancer patients, it is of great importance to reveal the molecular pathways and …

The interplay between microRNAs (miRNAs) and pluripotency transcription factors (TFs)
orchestrates the acquisition of cancer stem cell (CSC) features during the course of …

One of the main problems with the treatment of metastatic prostate cancer is that, despite an
initial positive response, the majority of patients develop resistance and progress. In …

Prostate cancer (PCa) is known as one of the most prevalent malignancies globally and is
not yet curable owing to its progressive nature. It has been well documented that Genetic …

Krüppel-like factor 4 (KLF4) is a transcription factor highly conserved in evolution. It is
particularly well known for its role in inducing pluripotent stem cells. In addition, KLF4 plays …

Cisplatin is an extensively used chemotherapeutic substance for various types of human
malignancies including sarcomas, carcinomas and lymphomas. Yet, the vast application of …

Cisplatin is a standard treatment for prostate cancer, which is the third leading cause of
cancer-related deaths among men globally. However, patients who have undergone …

Abstract Background miR‐148‐3p and miR‐152‐3p as the tumor suppressors have been
reported in various cancer types. Our study is aimed to discuss the synergistic effect of miR …

Tamoxifen (TAM) resistance is a significant clinical challenge in endocrine therapies for
estrogen receptor (ER)‐positive breast cancer patients. Cullin 4B (CUL4B), which acts as a …