A review of the biological role of miRNAs in prostate cancer suppression and progression
Prostate cancer (PC) is the third-leading cause of cancer-related deaths worldwide.
Although the current treatment strategies are progressing rapidly, PC is still representing a …
Although the current treatment strategies are progressing rapidly, PC is still representing a …
[HTML][HTML] Elucidating role of reactive oxygen species (ROS) in cisplatin chemotherapy: a focus on molecular pathways and possible therapeutic strategies
The failure of chemotherapy is a major challenge nowadays, and in order to ensure effective
treatment of cancer patients, it is of great importance to reveal the molecular pathways and …
treatment of cancer patients, it is of great importance to reveal the molecular pathways and …
[HTML][HTML] Reciprocal interplays between MicroRNAs and pluripotency transcription factors in dictating stemness features in human cancers
The interplay between microRNAs (miRNAs) and pluripotency transcription factors (TFs)
orchestrates the acquisition of cancer stem cell (CSC) features during the course of …
orchestrates the acquisition of cancer stem cell (CSC) features during the course of …
Mechanisms of docetaxel resistance in prostate cancer: The key role played by miRNAs
M Rizzo - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
One of the main problems with the treatment of metastatic prostate cancer is that, despite an
initial positive response, the majority of patients develop resistance and progress. In …
initial positive response, the majority of patients develop resistance and progress. In …
Prostate cancer and microRNAs: New insights into apoptosis
J Gupta, WK Abdulsahib, AT Jalil, DS Kareem… - … -Research and Practice, 2023 - Elsevier
Prostate cancer (PCa) is known as one of the most prevalent malignancies globally and is
not yet curable owing to its progressive nature. It has been well documented that Genetic …
not yet curable owing to its progressive nature. It has been well documented that Genetic …
[HTML][HTML] Recent discoveries on the involvement of Krüppel-like factor 4 in the most common cancer types
Krüppel-like factor 4 (KLF4) is a transcription factor highly conserved in evolution. It is
particularly well known for its role in inducing pluripotent stem cells. In addition, KLF4 plays …
particularly well known for its role in inducing pluripotent stem cells. In addition, KLF4 plays …
LncRNAs and miRNAs participate in determination of sensitivity of cancer cells to cisplatin
Cisplatin is an extensively used chemotherapeutic substance for various types of human
malignancies including sarcomas, carcinomas and lymphomas. Yet, the vast application of …
malignancies including sarcomas, carcinomas and lymphomas. Yet, the vast application of …
[HTML][HTML] tRNALys-Derived Fragment Alleviates Cisplatin-Induced Apoptosis in Prostate Cancer Cells
Cisplatin is a standard treatment for prostate cancer, which is the third leading cause of
cancer-related deaths among men globally. However, patients who have undergone …
cancer-related deaths among men globally. However, patients who have undergone …
miR‐148‐3p and miR‐152‐3p synergistically regulate prostate cancer progression via repressing KLF4
F Feng, H Liu, A Chen, Q Xia, Y Zhao… - Journal of cellular …, 2019 - Wiley Online Library
Abstract Background miR‐148‐3p and miR‐152‐3p as the tumor suppressors have been
reported in various cancer types. Our study is aimed to discuss the synergistic effect of miR …
reported in various cancer types. Our study is aimed to discuss the synergistic effect of miR …
CUL4B renders breast cancer cells tamoxifen‐resistant via miR‐32‐5p/ER‐α36 axis
Y Wang, X Pan, Y Li, R Wang, Y Yang… - The Journal of …, 2021 - Wiley Online Library
Tamoxifen (TAM) resistance is a significant clinical challenge in endocrine therapies for
estrogen receptor (ER)‐positive breast cancer patients. Cullin 4B (CUL4B), which acts as a …
estrogen receptor (ER)‐positive breast cancer patients. Cullin 4B (CUL4B), which acts as a …