[HTML][HTML] HTLV-1 infection and pathogenesis: new insights from cellular and animal models

G Forlani, M Shallak, RS Accolla… - International Journal of …, 2021 - mdpi.com
Since the discovery of the human T-cell leukemia virus-1 (HTLV-1), cellular and animal
models have provided invaluable contributions in the knowledge of viral infection …

Regulation of HTLV-1 transformation

KJ Ernzen, AR Panfil - Bioscience reports, 2022 - portlandpress.com
Human T-cell leukemia virus type 1 (HTLV-1) is the only identified oncogenic human
retrovirus. HTLV-1 infects approximately 5–10 million people worldwide and is the infectious …

Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)

S Ahmadi Ghezeldasht, DJ Blackbourn… - Critical Reviews in …, 2023 - Taylor & Francis
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy of CD4+ T
lymphocytes caused by human T lymphotropic virus type-1 (HTLV-1) infection. HTLV-1 was …

[HTML][HTML] Human T-Cell Leukemia Virus Type 1 Oncogenesis between Active Expression and Latency: A Possible Source for the Development of Therapeutic Targets

F Marino-Merlo, S Grelli, A Mastino, M Lai… - International Journal of …, 2023 - mdpi.com
The human T-cell leukemia virus type 1 (HTLV-1) is the only known human oncogenic
retrovirus. HTLV-1 can cause a type of cancer called adult T-cell leukemia/lymphoma (ATL) …

[HTML][HTML] Interplay between innate immunity and the viral oncoproteins Tax and HBZ in the pathogenesis and therapeutic response of HTLV-1 associated adult T cell …

H El Hajj, A Bazarbachi - Frontiers in Immunology, 2022 - frontiersin.org
The Human T-cell Leukemia virus type 1 (HTLV-1) causes an array of pathologies, the most
aggressive of which is adult T-cell leukemia (ATL), a fatal blood malignancy with dismal …

[HTML][HTML] The endogenous HBZ interactome in ATL leukemic cells reveals an unprecedented complexity of host interacting partners involved in RNA splicing

M Shallak, T Alberio, M Fasano, M Monti… - Frontiers in …, 2022 - frontiersin.org
Adult T-cell leukemia/lymphoma (ATL) is a T-cell lymphoproliferative neoplasm caused by
the human T-cell leukemia virus type 1 (HTLV-1). Two viral proteins, Tax-1 and HBZ play …

[HTML][HTML] Mechanisms of innate immune sensing of HTLV-1 and viral immune evasion

S Mohanty, EW Harhaj - Pathogens, 2023 - mdpi.com
Human T lymphotropic virus-1 (HTLV-1) was the first identified oncoretrovirus, which infects
and establishes a persistent infection in approximately 10–20 million people worldwide …

Novel insights into human T‐lymphotropic virus type‐1 (HTLV‐1) pathogenesis‐host interactions in the manifestation of HTLV‐1‐associated myelopathy/tropical …

S Ahmadi Ghezeldasht, A Mosavat… - Reviews in Medical …, 2024 - Wiley Online Library
Human T‐lymphotropic virus type‐1 (HTLV‐1) was the first discovered human oncogenic
retrovirus, the etiological agent of two serious diseases have been identified as adult T‐cell …

[HTML][HTML] Hijacking Host Immunity by the Human T-Cell Leukemia Virus Type-1: Implications for Therapeutic and Preventive Vaccines

CA Pise-Masison, G Franchini - Viruses, 2022 - mdpi.com
Human T-cell Leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma
(ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and other …

Cannabinoid receptors as new targets for HTLV-1 associated myelopathy (HAM/TSP) treatment

A Fadaee, FS Mohammadi, N Ariaee… - Multiple Sclerosis and …, 2024 - Elsevier
Abstract Background/Aim The roles of endocannabinoids are described in immune
modulation and neuroprotection. HTLV-1-associated myelopathy (HAM/TSP) is an …