Synopsis Desflurane is a halogenated ether inhalation general anaesthetic agent with low
solubility in blood and body tissues, and approximately one-fifth the potency of isoflurane …

Background Three strategies were employed to better define the afferent site (s) at which
desflurane initiates its neurocirculatory activation. Methods Young (aged 19-28 yr) healthy …

Conclusion The use of α 2 agonists, either alone or in combination, is becoming widespread
in anaesthesia. The original enthusiasm for this class of compound for its plethora of …

Study Objective: To determine the effects of oral clonidine premedication on hemodynamic
changes during the entire course of ketamine anesthesia and incidence of postoperative …

Background Airway irritation was hypothesized to trigger the transient cardiovascular
stimulation associated with desflurane. The authors administered desflurane during …

Background Epidural anesthesia is sometimes initiated during general anesthesia, yet few
data exist concerning efficacy of epinephrine-containing test doses. Methods Thirty-six …

The efficacy of an epinephrine test dose during epidural and combined epidural-general
anesthesia is unknown. Thirty-two patients were randomized to receive 2% lidocaine at …

objective: The objective of this study was to examine the dose-related effects of desflurane
and isoflurane on systemic vascular resistance during hypothermic cardiopulmonary …

Purpose: The volatile anesthetic desflurane has been associated with neurocirculatory
responses that have been relatively refractory to adjuvant treatment. We have employed …

Background: Desflurane inhalation is associated with sympathetic activation and
concomitant increase in heart rate in humans and experimental animals. There is, however …