A global view of the interplay between non-alcoholic fatty liver disease and diabetes

N Stefan, K Cusi - The lancet Diabetes & endocrinology, 2022 - thelancet.com
Non-alcoholic fatty liver disease (NAFLD) has become an epidemic, much like other non-
communicable diseases (NCDs), such as cancer, obesity, diabetes, and cardiovascular …

[HTML][HTML] A narrative review: CXC chemokines influence immune surveillance in obesity and obesity-related diseases: Type 2 diabetes and nonalcoholic fatty liver …

A Ullah, A Ud Din, W Ding, Z Shi, S Pervaz… - Reviews in Endocrine …, 2023 - Springer
Adipose tissue develops lipids, aberrant adipokines, chemokines, and pro-inflammatory
cytokines as a consequence of the low-grade systemic inflammation that characterizes …

[HTML][HTML] Major roles of kupffer cells and macrophages in NAFLD development

SJ Park, J Garcia Diaz, E Um, YS Hahn - Frontiers in Endocrinology, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is an important public health problem with growing
numbers of NAFLD patients worldwide. Pathological conditions are different in each stage of …

Combined with multiplex and network analysis to reveal the key genes and mechanisms of nonalcoholic fatty liver disease

Z Yang, X Han, K Wang, J Fang, Z Wang… - International …, 2023 - Elsevier
Abstract Background and Aims Non-alcoholic fatty liver disease (NAFLD) has become a
significant cause of chronic liver disease in developed countries, as a result of the worldwide …

The therapeutic potential of immunoengineering for systemic autoimmunity

DA McBride, RM Jones, N Bottini… - Nature Reviews …, 2024 - nature.com
Disease-modifying drugs have transformed the treatment options for many systemic
autoimmune diseases. However, an evolving understanding of disease mechanisms, which …

Impaired hepatic lipid metabolism and biomarkers in fatty liver diseases

FS Teixeira, LL Pimentel, ME Pintado… - Biochimie, 2023 - Elsevier
The liver plays a crucial role in lipid metabolism and metabolic homeostasis. Non-Alcoholic
Fatty Liver Disease (NAFLD) is the most common chronic liver disease worldwide and …

[HTML][HTML] Non-alcoholic fatty liver disease and liver secretome

MS Khan, C Lee, SG Kim - Archives of Pharmacal Research, 2022 - Springer
Metabolism of carbohydrates and lipids and protein degradation occurs in the liver and
contributes to the body's homeostasis by secreting a variety of mediators. Any imbalance in …

Noninvasive assessment of organ-specific and shared pathways in multi-organ fibrosis using T1 mapping

V Nauffal, MDR Klarqvist, MC Hill, DF Pace… - Nature Medicine, 2024 - nature.com
Fibrotic diseases affect multiple organs and are associated with morbidity and mortality. To
examine organ-specific and shared biologic mechanisms that underlie fibrosis in different …

[HTML][HTML] Investigation of the effect of curcumin on protein targets in NAFLD using bioinformatic analysis

A Mahmoudi, AE Butler, M Majeed, M Banach… - Nutrients, 2022 - mdpi.com
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder.
Defects in function/expression of genes/proteins are critical in initiation/progression of …

Expression of IGF-1 receptor and GH receptor in hepatic tissue of patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

SA Osganian, S Subudhi, R Masia, HK Drescher… - Growth Hormone & IGF …, 2022 - Elsevier
Abstract Objective The GH and IGF-1 axis is a candidate disease-modifying target in
nonalcoholic fatty liver disease (NAFLD) given its lipolytic, anti-inflammatory and anti-fibrotic …