Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Malaria is a mosquito-borne disease caused by protozoan parasites of the genus
Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …

Plasmodium falciparum VAR2CSA binds to chondroitin sulfate A (CSA) on the surface of the
syncytiotrophoblast during placental malaria. This interaction facilitates placental …

All malaria infections are harmful to both the pregnant mother and the developing fetus. One
in ten maternal deaths in malaria endemic countries are estimated to result from …

Background Capsid virus-like particles (cVLP) have proven safe and immunogenic and can
be a versatile platform to counter pandemics. We aimed to clinically test a modular cVLP …

Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

Like any other microorganism, pathogenic protozoan parasites rely heavily on
glycoconjugates and glycan binding proteins to protect themselves from the environment …

Placental malaria can have severe consequences for both mother and child and effective
vaccines are lacking. Parasite-infected red blood cells sequester in the placenta through …

In areas where Plasmodium falciparum transmission is endemic, clinical immunity against
malaria is progressively acquired during childhood and adults are usually protected against …

An estimated 10 million people developed tuberculosis (TB) disease in 2019 which
underscores the need for a vaccine that prevents disease and reduces transmission. The …