[HTML][HTML] Prophylactic efficacy against Mycobacterium tuberculosis using ID93 and lipid-based adjuvant formulations in the mouse model
SL Baldwin, VA Reese, SE Larsen, E Beebe… - Plos one, 2021 - journals.plos.org
An estimated 10 million people developed tuberculosis (TB) disease in 2019 which
underscores the need for a vaccine that prevents disease and reduces transmission. The …
underscores the need for a vaccine that prevents disease and reduces transmission. The …
No sweet deal: the antibody-mediated immune response to malaria
L Hviid, M Lopez-Perez, MD Larsen, G Vidarsson - Trends in parasitology, 2022 - cell.com
IgG antibodies are key effector molecules in acquired immunity to Plasmodium falciparum
malaria, and the PfEMP1 adhesins expressed on the surface of the infected erythrocytes are …
malaria, and the PfEMP1 adhesins expressed on the surface of the infected erythrocytes are …
[HTML][HTML] A Reproducible and Scalable Process for Manufacturing a Pfs48/45 Based Plasmodium falciparum Transmission-Blocking Vaccine
SK Singh, J Plieskatt, BK Chourasia… - Frontiers in …, 2021 - frontiersin.org
The cysteine-rich Pfs48/45 protein, a Plasmodium falciparum sexual stage surface protein,
has been advancing as a candidate antigen for a transmission-blocking vaccine (TBV) for …
has been advancing as a candidate antigen for a transmission-blocking vaccine (TBV) for …
Vector-borne diseases in pregnancy
B O'Kelly, JS Lambert - Therapeutic advances in infectious …, 2020 - journals.sagepub.com
Vector-borne infections cause a significant proportion of world-wide morbidity and mortality
and many are increasing in incidence. This is due to a combination of factors, primarily …
and many are increasing in incidence. This is due to a combination of factors, primarily …
[HTML][HTML] Placental malaria
Abstract Purpose of Review Placental malaria is the primary mechanism through which
malaria in pregnancy causes adverse perinatal outcomes. This review summarizes recent …
malaria in pregnancy causes adverse perinatal outcomes. This review summarizes recent …
Correlates of malaria vaccine efficacy
DI Stanisic, MBB McCall - Expert Review of Vaccines, 2021 - Taylor & Francis
Introduction: An effective vaccine against malaria forms a global health priority. Both
naturally acquired immunity and sterile protection induced by irradiated sporozoite …
naturally acquired immunity and sterile protection induced by irradiated sporozoite …
[HTML][HTML] A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
JYA Doritchamou, JP Renn, L Hviid, PE Duffy - PLoS Pathogens, 2023 - journals.plos.org
VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of
infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous …
infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous …
[HTML][HTML] Interplay of diverse adjuvants and nanoparticle presentation of native-like HIV-1 envelope trimers
K Sliepen, E Schermer, I Bontjer, JA Burger, RF Lévai… - npj Vaccines, 2021 - nature.com
The immunogenicity of HIV-1 envelope (Env) trimers is generally poor. We used the
clinically relevant ConM SOSIP trimer to compare the ability of different adjuvants (squalene …
clinically relevant ConM SOSIP trimer to compare the ability of different adjuvants (squalene …
Low dose recombinant full-length circumsporozoite protein-based Plasmodium falciparum vaccine is well-tolerated and highly immunogenic in phase 1 first-in-human …
DAJ Friedman-Klabanoff, AA Berry, MA Travassos… - Vaccine, 2021 - Elsevier
Plasmodium falciparum circumsporozoite protein (CSP) is a major sporozoite surface
protein and a key target of pre-erythrocytic malaria subunit vaccines. A full-length …
protein and a key target of pre-erythrocytic malaria subunit vaccines. A full-length …
[HTML][HTML] Recent clinical trials inform the future for malaria vaccines
Recent clinical trials inform the future for malaria vaccines | Communications Medicine Skip to
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