An estimated 10 million people developed tuberculosis (TB) disease in 2019 which
underscores the need for a vaccine that prevents disease and reduces transmission. The …

IgG antibodies are key effector molecules in acquired immunity to Plasmodium falciparum
malaria, and the PfEMP1 adhesins expressed on the surface of the infected erythrocytes are …

The cysteine-rich Pfs48/45 protein, a Plasmodium falciparum sexual stage surface protein,
has been advancing as a candidate antigen for a transmission-blocking vaccine (TBV) for …

Vector-borne infections cause a significant proportion of world-wide morbidity and mortality
and many are increasing in incidence. This is due to a combination of factors, primarily …

Abstract Purpose of Review Placental malaria is the primary mechanism through which
malaria in pregnancy causes adverse perinatal outcomes. This review summarizes recent …

Introduction: An effective vaccine against malaria forms a global health priority. Both
naturally acquired immunity and sterile protection induced by irradiated sporozoite …

VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of
infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous …

The immunogenicity of HIV-1 envelope (Env) trimers is generally poor. We used the
clinically relevant ConM SOSIP trimer to compare the ability of different adjuvants (squalene …

Plasmodium falciparum circumsporozoite protein (CSP) is a major sporozoite surface
protein and a key target of pre-erythrocytic malaria subunit vaccines. A full-length …

Recent clinical trials inform the future for malaria vaccines | Communications Medicine Skip to
main content Thank you for visiting nature.com. You are using a browser version with limited …