[HTML][HTML] Malaria vaccines: facing unknowns
NMQ Palacpac, T Horii - F1000Research, 2020 - ncbi.nlm.nih.gov
Much of the gain in malaria control, in terms of regional achievements in restricting
geographical spread and reducing malaria cases and deaths, can be attributed to large …
geographical spread and reducing malaria cases and deaths, can be attributed to large …
[HTML][HTML] Comprehensive overview of vaccination during pregnancy in Europe
Vaccinations during pregnancy can protect the mother from several infections, thus blocking
vertical transmission. Furthermore, through passive antibody transfer, the newborn can be …
vertical transmission. Furthermore, through passive antibody transfer, the newborn can be …
A single full-length VAR2CSA ectodomain variant purifies broadly neutralizing antibodies against placental malaria isolates
JYA Doritchamou, JP Renn, B Jenkins, A Mahamar… - Elife, 2022 - elifesciences.org
Placental malaria (PM) is a deadly syndrome most frequent and severe in first pregnancies.
PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that …
PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that …
[HTML][HTML] Re-orienting anti-malarial drug development to better serve pregnant women
M El Gaaloul, B Tornesi, F Lebus, D Reddy… - Malaria Journal, 2022 - Springer
Malaria is one of the most serious infectious diseases affecting predominantly low-and
middle-income countries, where pregnant women are among the populations at risk. There …
middle-income countries, where pregnant women are among the populations at risk. There …
A review of combination adjuvants for malaria vaccines: a promising approach for vaccine development
S Pirahmadi, S Zakeri, ND Djadid, AA Mehrizi - International journal for …, 2021 - Elsevier
It is obvious that there is a critical need for an efficient malaria vaccine to accelerate malaria
eradication. Currently, recombinant subunit vaccination against malaria using proteins and …
eradication. Currently, recombinant subunit vaccination against malaria using proteins and …
[HTML][HTML] Unveiling the sugary secrets of Plasmodium parasites
F Goerdeler, PH Seeberger, O Moscovitz - Frontiers in microbiology, 2021 - frontiersin.org
Plasmodium parasites cause malaria disease, one of the leading global health burdens for
humanity, infecting hundreds of millions of people each year. Different glycans on the …
humanity, infecting hundreds of millions of people each year. Different glycans on the …
[HTML][HTML] Preclinical immunogenicity and safety of the cGMP-grade placental malaria vaccine PRIMVAC
A Chêne, S Gangnard, A Guadall, H Ginisty, O Leroy… - …, 2019 - thelancet.com
Background VAR2CSA is the lead antigen for developing a vaccine that would protect
pregnant women against placental malaria. A multi-system feasibility study has identified E …
pregnant women against placental malaria. A multi-system feasibility study has identified E …
Future vaccines in pregnancy
D Vress - Best Practice & Research Clinical Obstetrics & …, 2021 - Elsevier
Vaccination in pregnancy provides an important opportunity to target illnesses that are
known to impact pregnant women, fetal development, and newborns in particular. The ability …
known to impact pregnant women, fetal development, and newborns in particular. The ability …
[HTML][HTML] The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum
W Wang, Z Wang, X Yang, Y Gao, X Zhang, L Cao… - Cell discovery, 2021 - nature.com
Dear Editor, Pregnancy-associated malaria (PAM) threatened more than one million women
and their infants in endemic regions in 2019. This resulted in maternal anemia, stillbirth, and …
and their infants in endemic regions in 2019. This resulted in maternal anemia, stillbirth, and …
Multi-functional antibody profiling for malaria vaccine development and evaluation
Introduction A vaccine would greatly accelerate current global efforts toward malaria
elimination. While a partially efficacious vaccine has been achieved for Plasmodium …
elimination. While a partially efficacious vaccine has been achieved for Plasmodium …